7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
7,8,8a,9a-Tetrahydrobenzo(10,11)chryseno (3,4-b)oxirene-7,8-diol. A benzopyrene derivative with carcinogenic and mutagenic activity.
MeSH Number(s)
D02.455.426.559.847.799.306.400.350
D04.615.799.306.400.350
Concept/Terms
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide- 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
- 7,8-Dihydroxy-9,10-Epoxy-7,8,9,10-Tetrahydrobenzo(a)pyrene
- BPDE
- Benzo(a)pyrene 7,8-Dihydrodiol 9,10-Epoxide
- Benzo(a)pyrene-7,8-diol 9,10-Epoxide
- 7,8-BaP-9,10-Diol Epoxide
- Anti-BaPDE
- Anti BaPDE
Below are MeSH descriptors whose meaning is more general than "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide".
- Chemicals and Drugs [D]
- Organic Chemicals [D02]
- Hydrocarbons [D02.455]
- Hydrocarbons, Cyclic [D02.455.426]
- Hydrocarbons, Aromatic [D02.455.426.559]
- Polycyclic Hydrocarbons, Aromatic [D02.455.426.559.847]
- Pyrenes [D02.455.426.559.847.799]
- Benzopyrenes [D02.455.426.559.847.799.306]
- Dihydroxydihydrobenzopyrenes [D02.455.426.559.847.799.306.400]
- 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide [D02.455.426.559.847.799.306.400.350]
- Polycyclic Compounds [D04]
- Polycyclic Hydrocarbons, Aromatic [D04.615]
- Pyrenes [D04.615.799]
- Benzopyrenes [D04.615.799.306]
- Dihydroxydihydrobenzopyrenes [D04.615.799.306.400]
- 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide [D04.615.799.306.400.350]
Below are MeSH descriptors whose meaning is more specific than "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide".
This graph shows the total number of publications written about "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide" by people in Harvard Catalyst Profiles by year, and whether "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 2 | 0 | 2 |
| 2002 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
Below are the most recent publications written about "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide" by people in Profiles.
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Cyanidin-3-glucoside suppresses B[a]PDE-induced cyclooxygenase-2 expression by directly inhibiting Fyn kinase activity. Biochem Pharmacol. 2011 Jul 15; 82(2):167-74.
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FOXO3 encodes a carcinogen-activated transcription factor frequently deleted in early-stage lung adenocarcinoma. Cancer Res. 2010 Aug 01; 70(15):6205-15.
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Spectral differentiation and immunoaffinity capillary electrophoresis separation of enantiomeric benzo(a)pyrene diol epoxide-derived DNA adducts. Chem Res Toxicol. 2007 Aug; 20(8):1192-9.
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Leukocyte polycyclic aromatic hydrocarbon-DNA adduct formation and colorectal adenoma. Carcinogenesis. 2007 Jul; 28(7):1426-9.
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CYP1A1 in polycyclic aromatic hydrocarbon-induced B lymphocyte growth suppression. Biochem Biophys Res Commun. 2006 Mar 31; 342(1):227-35.
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The p53 tumour suppressor gene and the tobacco industry: research, debate, and conflict of interest. Lancet. 2005 Feb 5-11; 365(9458):531-40.
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Cell cycle checkpoints, DNA damage/repair, and lung cancer risk. Cancer Res. 2005 Jan 01; 65(1):349-57.
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Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint. Mol Cell Biol. 2003 Feb; 23(3):791-803.
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Activation of the aromatic hydrocarbon receptor pathway is not sufficient for transcriptional repression of BRCA-1: requirements for metabolism of benzo[a]pyrene to 7r,8t-dihydroxy-9t,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. Cancer Res. 2002 Jan 01; 62(1):113-21.
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Disruption of cell cycle kinetics by benzo[a]pyrene: inverse expression patterns of BRCA-1 and p53 in MCF-7 cells arrested in S and G2. Neoplasia. 2000 Sep-Oct; 2(5):460-70.