Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

25-Hydroxyvitamin D3 1-alpha-Hydroxylase

"25-Hydroxyvitamin D3 1-alpha-Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A mitochondrial cytochrome P450 enzyme that catalyzes the 1-alpha-hydroxylation of 25-hydroxyvitamin D3 (also known as 25-hydroxycholecalciferol) in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP27B1 gene, converts 25-hydroxyvitamin D3 to 1-alpha,25-dihydroxyvitamin D3 which is the active form of VITAMIN D in regulating bone growth and calcium metabolism. This enzyme is also active on plant 25-hydroxyvitamin D2 (ergocalciferol).


This graph shows the total number of publications written about "25-Hydroxyvitamin D3 1-alpha-Hydroxylase" by people in Harvard Catalyst Profiles by year, and whether "25-Hydroxyvitamin D3 1-alpha-Hydroxylase" was a major or minor topic of these publication.
Bar chart showing 49 publications over 16 distinct years, with a maximum of 7 publications in 2009 and 2010
To see the data from this visualization as text, click here.
Related Networks
People
Explore
_
Similar Concepts
_
Top Journals 
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.