Harvard Catalyst Profiles

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2,3-Diphosphoglycerate

"2,3-Diphosphoglycerate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)


This graph shows the total number of publications written about "2,3-Diphosphoglycerate" by people in Harvard Catalyst Profiles by year, and whether "2,3-Diphosphoglycerate" was a major or minor topic of these publication.
Bar chart showing 8 publications over 8 distinct years, with a maximum of 1 publications in 2000 and 2002 and 2003 and 2011 and 2012 and 2013 and 2014 and 2022
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.