Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

2',5'-Oligoadenylate Synthetase

"2',5'-Oligoadenylate Synthetase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
Definition  |  Details  |  More General Concepts  |  Related Concepts  |  More Specific Concepts
An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (RNase L) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions. EC 2.7.7.-.


publications
Timeline   |   Most Recent
This graph shows the total number of publications written about "2',5'-Oligoadenylate Synthetase" by people in Harvard Catalyst Profiles by year, and whether "2',5'-Oligoadenylate Synthetase" was a major or minor topic of these publication.
To see the data from this visualization as text,
Related Networks
People
Explore
_
Similar Concepts
_
Top Journals 
_
© 2025 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.