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11-beta-Hydroxysteroid Dehydrogenase Type 2

"11-beta-Hydroxysteroid Dehydrogenase Type 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

An high-affinity, NAD-dependent 11-beta-hydroxysteroid dehydrogenase that acts unidirectionally to catalyze the dehydrogenation of CORTISOL to CORTISONE. It is found predominantly in mineralocorticoid target tissues such as the KIDNEY; COLON; SWEAT GLANDS; and the PLACENTA. Absence of the enzyme leads to a fatal form of childhood hypertension termed, APPARENT MINERALOCORTICOID EXCESS SYNDROME.


This graph shows the total number of publications written about "11-beta-Hydroxysteroid Dehydrogenase Type 2" by people in Harvard Catalyst Profiles by year, and whether "11-beta-Hydroxysteroid Dehydrogenase Type 2" was a major or minor topic of these publication.
Bar chart showing 9 publications over 8 distinct years, with a maximum of 2 publications in 2008
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.