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mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.
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mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. J Clin Invest. 2011 Jun; 121(6):2181-96.
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PubMed
subject areas
Adaptor Proteins, Signal Transducing
Animals
Carrier Proteins
Cell Differentiation
Diabetes Mellitus, Type 2
Diabetic Nephropathies
Disease Models, Animal
Endoplasmic Reticulum
Enzyme Activation
Glomerular Basement Membrane
Glomerular Mesangium
Male
Membrane Proteins
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Mutant Strains
Multiprotein Complexes
Phosphorylation
Podocytes
Protein Processing, Post-Translational
Proteins
Ribosomal Protein S6 Kinases
Sirolimus
TOR Serine-Threonine Kinases
Tumor Suppressor Proteins
authors with profiles
David Joseph Kwiatkowski, M.D., Ph.D.