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PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.
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PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.
PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas. Nat Med. 2012 Nov; 18(11):1699-704.
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PubMed
subject areas
Adult
Animals
Benzamides
Cell Line, Tumor
Gene Expression Regulation, Neoplastic
Humans
Lymphoma, Large-Cell, Anaplastic
Mice
Mice, Transgenic
Molecular Targeted Therapy
Neoplasm Staging
Nuclear Proteins
Oncogene Protein p65(gag-jun)
Piperazines
Protein-Tyrosine Kinases
Pyrimidines
Receptor Protein-Tyrosine Kinases
Receptor, Platelet-Derived Growth Factor alpha
Receptor, Platelet-Derived Growth Factor beta
Remission Induction
Stem Cell Transplantation
Transcription Factor AP-1
Translocation, Genetic