Harvard Catalyst Profiles

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A phase 2 study of the KIT inhibitor XL820 in patients with advanced gastrointestinal stromal tumors (GIST) resistant to or intolerant of the tyrosine kinase inhibitors (TKI) imatinib and/or sunitinib

Wagner AJ, Yazji S, Morgan JA, Choy E, Shen A, George S, Cancilla M, Kaiser P, Tap W, Hohos M, O'Mara M,Demetri GD. A phase 2 study of the KIT inhibitor XL820 in patients with advanced gastrointestinal stromal tumors (GIST) resistant to or intolerant of the tyrosine kinase inhibitors (TKI) imatinib and/or sunitinib. Connective Tissue Oncology Society Annual Meeting. 2008.


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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.