Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy.
Huang Y, Yuan J, Righi E, Kamoun WS, Ancukiewicz M, Nezivar J, Santosuosso M, Martin JD, Martin MR, Vianello F, Leblanc P, Munn LL, Huang P, Duda DG, Fukumura D, Jain RK, Poznansky MC. Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17561-6.
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Dan Gabriel Duda, Ph.D., D.M.D.
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Lance Leon Munn, Ph.D.
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Rakesh K. Jain, Ph.D.
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Peigen Huang, M.D.
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Dai Fukumura, Ph.D., M.D.
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Pierre Regent Leblanc, Ph.D.
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Mark Poznansky, Ph.D., M.B.,Ch.B.