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Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase.
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Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase.
Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase. Nat Chem Biol. 2012 Feb 12; 8(3):311-7.
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subject areas
Amino Acyl-tRNA Synthetases
Animals
Cell Differentiation
Dose-Response Relationship, Drug
Enzyme Inhibitors
Humans
Mice
Mice, Inbred C57BL
Piperidines
Quinazolines
Quinazolinones
Structure-Activity Relationship
Th17 Cells
authors with profiles
Tracy Leigh Keller, Ph.D.
Dyann Fergus Wirth, Ph.D.
Ralph Mazitschek, Ph.D.
Malcolm Russell Whitman, Ph.D.