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C-Raf is required for the initiation of lung cancer by K-Ras(G12D).
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C-Raf is required for the initiation of lung cancer by K-Ras(G12D).
Karreth FA, Frese KK, DeNicola GM, Baccarini M, Tuveson DA. C-Raf is required for the initiation of lung cancer by K-Ras(G12D). Cancer Discov. 2011 Jul; 1(2):128-36.
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subject areas
Animals
Cell Growth Processes
Cell Transformation, Neoplastic
Epithelial Cells
Extracellular Signal-Regulated MAP Kinases
Fibroblasts
Lung
Lung Neoplasms
MAP Kinase Signaling System
Mesenchymal Stem Cells
Mice
Mice, 129 Strain
Mitogen-Activated Protein Kinases
Mutation
Proto-Oncogene Proteins B-raf
Proto-Oncogene Proteins c-raf
ras Proteins
Transformation, Genetic