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A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein.
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A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein.
A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein. J Biol Chem. 2005 Nov 04; 280(44):36895-904.
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PubMed
subject areas
Amyloid beta-Protein Precursor
Amyloid Precursor Protein Secretases
Animals
Aspartic Acid Endopeptidases
Cell Membrane
Cell Nucleus
Cells, Cultured
Cyclin-Dependent Kinases
Endopeptidases
Enzyme Inhibitors
Fluorescent Antibody Technique
Histone Acetyltransferases
Humans
Kidney
Membrane Proteins
Mice
Mice, Knockout
Mice, Transgenic
Microscopy, Confocal
Mutation
Nerve Tissue Proteins
Nuclear Proteins
Phosphorylation
Presenilin-1
Presenilin-2
Protein Structure, Tertiary
Purines
Receptors, Notch
Signal Transduction
Stem Cells
Subcellular Fractions
Transcription, Genetic
Transcriptional Activation
authors with profiles
Bruce A. Yankner, M.D.,Ph.D.