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Does surgery unfavourably perturb the "natural history" of early breast cancer by accelerating the appearance of distant metastases?

Baum M, Demicheli R, Hrushesky W, Retsky M. Does surgery unfavourably perturb the "natural history" of early breast cancer by accelerating the appearance of distant metastases? Eur J Cancer. 2005 Mar; 41(4):508-15.

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