Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma.
Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma. J Exp Med. 2012 Oct 22; 209(11):1985-2000.
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Animals
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Antibodies, Monoclonal
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Antibodies, Neutralizing
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Cell Hypoxia
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Cell Line, Tumor
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Cells, Cultured
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Galectin 1
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Gene Expression Regulation, Neoplastic
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HEK293 Cells
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Herpesvirus 8, Human
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Host-Pathogen Interactions
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Humans
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Immunoblotting
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Mice
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Mice, Inbred C57BL
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Mice, Knockout
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Mice, Nude
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Neovascularization, Pathologic
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Polysaccharides
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Protein Binding
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Reverse Transcriptase Polymerase Chain Reaction
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RNA Interference
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Sarcoma, Kaposi
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Xenograft Model Antitumor Assays