High-penetrance mouse model of acute promyelocytic leukemia with very low levels of PML-RARalpha expression.
High-penetrance mouse model of acute promyelocytic leukemia with very low levels of PML-RARalpha expression. Blood. 2003 Sep 01; 102(5):1857-65.
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Animals
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Antigens, CD34
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Antineoplastic Agents
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Cathepsin G
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Cathepsins
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Cell Differentiation
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Chromosomes, Mammalian
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Disease Models, Animal
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Female
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Gene Deletion
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Gene Dosage
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Humans
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Leukemia, Promyelocytic, Acute
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Male
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Mice
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Mice, Inbred C57BL
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Mice, Transgenic
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Neoplasm Proteins
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Oncogene Proteins, Fusion
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Penetrance
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Recombination, Genetic
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RNA, Messenger
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Serine Endopeptidases
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Tretinoin