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Synthesis and preliminary PET imaging of 11C and 18F isotopologues of the ROS1/ALK inhibitor lorlatinib.
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Synthesis and preliminary PET imaging of 11C and 18F isotopologues of the ROS1/ALK inhibitor lorlatinib.
Synthesis and preliminary PET imaging of 11C and 18F isotopologues of the ROS1/ALK inhibitor lorlatinib. Nat Commun. 2017 06 08; 8:15761.
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subject areas
Aminopyridines
Animals
Carbon Radioisotopes
Contrast Media
Fluorine Radioisotopes
Humans
Isotope Labeling
Lactams
Lactams, Macrocyclic
Macaca mulatta
Male
Mice
Positron-Emission Tomography
Protein-Tyrosine Kinases
Proto-Oncogene Proteins
Pyrazoles
Tissue Distribution
Xenograft Model Antitumor Assays
authors with profiles
Shadi Abdar Esfahani, M.D.
Marc D Normandin, Ph.D.
Dustin Wade Wooten, Ph.D.
Paul Gerard Guy Richardson, M.B.,B.S.
Georges El Fakhri, Ph.D.
Steven H. Liang, Ph.D.
Umar Mahmood, M.D., Ph.D.