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A substrate-based approach to convert SerpinB1 into a specific inhibitor of proteinase 3, the Wegener's granulomatosis autoantigen.

Jégot G, Derache C, Castella S, Lahouassa H, Pitois E, Jourdan ML, Remold-O'Donnell E, Kellenberger C, Gauthier F, Korkmaz B. A substrate-based approach to convert SerpinB1 into a specific inhibitor of proteinase 3, the Wegener's granulomatosis autoantigen. FASEB J. 2011 Sep; 25(9):3019-31.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.