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Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.
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Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. Blood. 2010 Dec 16; 116(25):5443-54.
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PubMed
subject areas
Animals
Blotting, Northern
Blotting, Western
Cell Transformation, Neoplastic
DNA Primers
Flow Cytometry
Gene Expression Regulation, Neoplastic
Ikaros Transcription Factor
Immunoglobulin J Recombination Signal Sequence-Binding Protein
Mice
Mice, Knockout
Mutation
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Promoter Regions, Genetic
Receptor, Notch1
Receptors, Notch
Reverse Transcriptase Polymerase Chain Reaction
RNA, Messenger
Sequence Deletion
Survival Rate
Transcriptional Activation
authors with profiles
Jon Christopher Aster, M.D.,Ph.D.