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Development of a fluorescence polarization based assay for histone deacetylase ligand discovery.
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Development of a fluorescence polarization based assay for histone deacetylase ligand discovery.
Development of a fluorescence polarization based assay for histone deacetylase ligand discovery. Bioorg Med Chem Lett. 2008 May 01; 18(9):2809-12.
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PubMed
subject areas
Biological Assay
Drug Evaluation, Preclinical
Enzyme Inhibitors
Fluorescence Resonance Energy Transfer
Fluorescent Dyes
Histone Deacetylase Inhibitors
Ligands
Substrate Specificity
authors with profiles
Ralph Mazitschek, Ph.D.
Dyann Fergus Wirth, Ph.D.
Jon Clardy, Ph.D.