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Can nicotine self-inhibition account for its low efficacy at the nicotinic acetylcholine receptor from Torpedo?

Tonner PH, Wood SC, Miller KW. Can nicotine self-inhibition account for its low efficacy at the nicotinic acetylcholine receptor from Torpedo? Mol Pharmacol. 1992 Nov; 42(5):890-7.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.