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Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors.
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Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors.
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors. Nat Chem Biol. 2016 10; 12(10):876-84.
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PubMed
subject areas
Anilides
CDC2 Protein Kinase
Cell Death
Cyclin-Dependent Kinases
Cysteine
DNA Damage
Humans
Protein Kinase Inhibitors
Pyrimidines
authors with profiles
Jarrod Marto, Ph.D.
Scott Ficarro, Ph.D.
Sarah Dixon-Clarke, Ph.D.