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The ins and outs of selective kinase inhibitor development.
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The ins and outs of selective kinase inhibitor development.
The ins and outs of selective kinase inhibitor development. Nat Chem Biol. 2015 Nov; 11(11):818-21.
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PubMed
subject areas
Allosteric Site
Catalytic Domain
Crystallography, X-Ray
Drug Approval
Drug Design
Drug Discovery
Humans
Protein Conformation
Protein Kinase Inhibitors
Protein Kinases
Quantitative Structure-Activity Relationship
Small Molecule Libraries
United States
United States Food and Drug Administration