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Multimodal treatment of perianal fistulas in Crohn's disease: seton versus anti-TNF versus advancement plasty (PISA): study protocol for a randomized controlled trial.

de Groof EJ, Buskens CJ, Ponsioen CY, Dijkgraaf MG, D'Haens GR, Srivastava N, van Acker GJ, Jansen JM, Gerhards MF, Dijkstra G, Lange JF, Witteman BJ, Kruyt PM, Pronk A, van Tuyl SA, Bodelier A, Crolla RM, West RL, Vrijland WW, Consten EC, Brink MA, Tuynman JB, de Boer NK, Breukink SO, Pierik MJ, Oldenburg B, van der Meulen AE, Bonsing BA, Spinelli A, Danese S, Sacchi M, Warusavitarne J, Hart A, Yassin NA, Kennelly RP, Cullen GJ, Winter DC, Hawthorne AB, Torkington J, Bemelman WA. Multimodal treatment of perianal fistulas in Crohn's disease: seton versus anti-TNF versus advancement plasty (PISA): study protocol for a randomized controlled trial. Trials. 2015 Aug 20; 16:366.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.