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Synthesis of Small 3-Fluoro- and 3,3-Difluoropyrrolidines Using Azomethine Ylide Chemistry.

McAlpine I, Tran-Dubé M, Wang F, Scales S, Matthews J, Collins MR, Nair SK, Nguyen M, Bian J, Alsina LM, Sun J, Zhong J, Warmus JS, O'Neill BT. Synthesis of Small 3-Fluoro- and 3,3-Difluoropyrrolidines Using Azomethine Ylide Chemistry. J Org Chem. 2015 Jul 17; 80(14):7266-74.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.