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Crystal cryocooling distorts conformational heterogeneity in a model Michaelis complex of DHFR.
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Crystal cryocooling distorts conformational heterogeneity in a model Michaelis complex of DHFR.
Crystal cryocooling distorts conformational heterogeneity in a model Michaelis complex of DHFR. Structure. 2014 Jun 10; 22(6):899-910.
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PubMed
subject areas
Cold Temperature
Crystallization
Crystallography, X-Ray
Escherichia coli
Escherichia coli Proteins
Models, Molecular
Molecular Dynamics Simulation
Protein Conformation
Protein Structure, Tertiary
Static Electricity
Tetrahydrofolate Dehydrogenase
authors with profiles
Gregory A. Petsko, Ph.D.