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A novel secondary DNA binding site in human topoisomerase I unravelled by using a 2D DNA origami platform.

Subramani R, Juul S, Rotaru A, Andersen FF, Gothelf KV, Mamdouh W, Besenbacher F, Dong M, Knudsen BR. A novel secondary DNA binding site in human topoisomerase I unravelled by using a 2D DNA origami platform. ACS Nano. 2010 Oct 26; 4(10):5969-77.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.