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Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells.
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Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells.
Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells. J Clin Invest. 2014 Jun; 124(6):2513-22.
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PubMed
subject areas
Adult
Animals
Autoimmunity
Case-Control Studies
Dinoprostone
Down-Regulation
Female
Gene Knockdown Techniques
Gene Silencing
Humans
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Middle Aged
Models, Immunological
Multiple Sclerosis
Nuclear Receptor Subfamily 1, Group F, Member 3
Phenotype
Promoter Regions, Genetic
Receptors, Prostaglandin E, EP2 Subtype
Signal Transduction
Th17 Cells
authors with profiles
Vijay Kumar Kuchroo, Ph.D.
David A. Hafler, M.D.