Harvard Catalyst Profiles

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TLR2 signaling depletes IRAK1 and inhibits induction of type I IFN by TLR7/9.

Liu YC, Simmons DP, Li X, Abbott DW, Boom WH, Harding CV. TLR2 signaling depletes IRAK1 and inhibits induction of type I IFN by TLR7/9. J Immunol. 2012 Feb 01; 188(3):1019-26.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.