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Cannabinoids induce pancreatic ß-cell death by directly inhibiting insulin receptor activation.
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Cannabinoids induce pancreatic ß-cell death by directly inhibiting insulin receptor activation.
Cannabinoids induce pancreatic ß-cell death by directly inhibiting insulin receptor activation. Sci Signal. 2012 Mar 20; 5(216):ra23.
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PubMed
subject areas
Analysis of Variance
Animals
bcl-Associated Death Protein
Blotting, Western
Cannabinoids
Cell Death
Cells, Cultured
DNA, Complementary
Enzyme-Linked Immunosorbent Assay
Fluorescent Antibody Technique
Humans
Immunoprecipitation
Insulin-Secreting Cells
Mice
Mice, Inbred C57BL
Mice, Knockout
Receptor, Cannabinoid, CB1
Receptor, Insulin
Reverse Transcriptase Polymerase Chain Reaction
Transfection
authors with profiles
Rohit N. Kulkarni, Ph.D., M.D.