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Leptin does not directly affect CNS serotonin neurons to influence appetite.

Lam DD, Leinninger GM, Louis GW, Garfield AS, Marston OJ, Leshan RL, Scheller EL, Christensen L, Donato J, Xia J, Evans ML, Elias C, Dalley JW, Burdakov DI, Myers MG, Heisler LK. Leptin does not directly affect CNS serotonin neurons to influence appetite. Cell Metab. 2011 May 04; 13(5):584-91.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.