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Presenilins and ?-secretase: structure, function, and role in Alzheimer Disease.
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Presenilins and ?-secretase: structure, function, and role in Alzheimer Disease.
Presenilins and ?-secretase: structure, function, and role in Alzheimer Disease. Cold Spring Harb Perspect Med. 2012 Jan; 2(1):a006304.
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PubMed
subject areas
Alzheimer Disease
Amyloid beta-Peptides
Amyloid Precursor Protein Secretases
Drug Discovery
Enzyme Inhibitors
Humans
Mutation, Missense
Presenilins
Receptors, Notch
Structure-Activity Relationship