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Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin kappa-chain locus.
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Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin kappa-chain locus.
Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin kappa-chain locus. Nat Immunol. 2007 Jul; 8(7):715-22.
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PubMed
subject areas
Alleles
Animals
Antibody Diversity
B-Lymphocytes
DNA Methylation
Epigenesis, Genetic
Gene Rearrangement, B-Lymphocyte
Genetic Markers
Humans
Immunoglobulin kappa-Chains
Immunoglobulin Variable Region
Mice
Mice, Transgenic
Somatic Hypermutation, Immunoglobulin
authors with profiles
Frederick W. Alt, Ph.D.
Raul Mostoslavsky, Ph.D., M.D.