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Structure-activity relationship study of tricyclic necroptosis inhibitors.
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Structure-activity relationship study of tricyclic necroptosis inhibitors.
Jagtap PG, Degterev A, Choi S, Keys H, Yuan J, Cuny GD. Structure-activity relationship study of tricyclic necroptosis inhibitors. J Med Chem. 2007 Apr 19; 50(8):1886-95.
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subject areas
Caspases
Cell Line
Fas-Associated Death Domain Protein
Heterocyclic Compounds, 3-Ring
Humans
Indazoles
Necrosis
Pyrazoles
Stereoisomerism
Structure-Activity Relationship
Tumor Necrosis Factor-alpha