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The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties.
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The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties.
The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties. Proc Natl Acad Sci U S A. 1996 Feb 06; 93(3):1044-8.
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PubMed
subject areas
Acute Disease
Animals
Blast Crisis
Calcium-Calmodulin-Dependent Protein Kinases
Cell Division
Cell Line
Cell Transformation, Neoplastic
Chimera
Chromosome Mapping
Chromosomes, Human, Pair 21
Chromosomes, Human, Pair 3
Core Binding Factor Alpha 2 Subunit
DNA-Binding Proteins
Glycogen Synthase Kinase 3
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Leukemia, Myeloid
Mice
Myelodysplastic Syndromes
Neoplasm Proteins
Proto-Oncogene Proteins
Rats
Receptor, Macrophage Colony-Stimulating Factor
Recombinant Fusion Proteins
Recombinant Proteins
Ribosomal Proteins
RNA-Binding Proteins
Transcription Factors
Transfection
Translocation, Genetic
authors with profiles
Daniel Geoffrey Tenen, M.D.