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p53 suppresses c-Myb-induced trans-activation and transformation by recruiting the corepressor mSin3A.
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p53 suppresses c-Myb-induced trans-activation and transformation by recruiting the corepressor mSin3A.
p53 suppresses c-Myb-induced trans-activation and transformation by recruiting the corepressor mSin3A. J Biol Chem. 2004 Dec 31; 279(53):55393-400.
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subject areas
Apoptosis
Cell Line
Cell Proliferation
DNA
Down-Regulation
Electrophoresis, Polyacrylamide Gel
Gene Expression Regulation
Glutathione Transferase
Hematopoietic Stem Cells
Humans
Immunoprecipitation
Interleukin-6
Luciferases
Models, Biological
Oligonucleotide Array Sequence Analysis
Protein Binding
Protein Structure, Tertiary
Proto-Oncogene Proteins c-myb
Repressor Proteins
RNA
Sin3 Histone Deacetylase and Corepressor Complex
Transcription, Genetic
Transcriptional Activation
Transfection
Tumor Suppressor Protein p53
Up-Regulation