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FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis.
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FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis.
FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis. Cancer Cell. 2010 Nov 16; 18(5):472-84.
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PubMed
subject areas
Animals
Apoptosis
Basic Helix-Loop-Helix Transcription Factors
Carcinoma, Renal Cell
Forkhead Transcription Factors
Gene Expression Regulation, Neoplastic
Humans
Kidney Neoplasms
Mice
MicroRNAs
Multiprotein Complexes
Proteins
Proto-Oncogene Proteins c-myc
Signal Transduction
TOR Serine-Threonine Kinases
Transcriptional Activation
Tumor Cells, Cultured
Tumor Suppressor Proteins
authors with profiles
William George Kaelin, M.D.
Sabina Signoretti, M.D.
David Joseph Kwiatkowski, M.D., Ph.D.