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PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos.
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PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos.
PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos. Nature. 2012 Jun 03; 486(7403):415-9.
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subject areas
5-Methylcytosine
Animals
Chromatin
Chromosomal Proteins, Non-Histone
Cytosine
Dioxygenases
DNA Methylation
DNA-Binding Proteins
Embryo, Mammalian
Embryonic Development
Female
Genomic Imprinting
Histones
Lysine
Male
Methylation
Mice
Protein Binding
Proto-Oncogene Proteins
ras-GRF1
Repressor Proteins
RNA, Untranslated
Spermatozoa