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Nicorandil attenuates monocrotaline-induced vascular endothelial damage and pulmonary arterial hypertension.
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Nicorandil attenuates monocrotaline-induced vascular endothelial damage and pulmonary arterial hypertension.
Nicorandil attenuates monocrotaline-induced vascular endothelial damage and pulmonary arterial hypertension. PLoS One. 2012; 7(3):e33367.
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PubMed
subject areas
Animals
Antihypertensive Agents
Apoptosis
Blotting, Western
Caspase 3
Cells, Cultured
Drug Therapy, Combination
Endothelium, Vascular
Enzyme Inhibitors
Glyburide
Humans
Hypertension, Pulmonary
Injections, Intraperitoneal
Male
MAP Kinase Signaling System
Monocrotaline
NG-Nitroarginine Methyl Ester
Nicorandil
Phosphatidylinositol 3-Kinases
Proto-Oncogene Proteins c-akt
Random Allocation
Rats
Rats, Sprague-Dawley
Signal Transduction
Ventricular Pressure