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HIF-1a activation mediates resistance to anti-angiogenic therapy in neuroblastoma xenografts.
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HIF-1a activation mediates resistance to anti-angiogenic therapy in neuroblastoma xenografts.
HIF-1a activation mediates resistance to anti-angiogenic therapy in neuroblastoma xenografts. J Pediatr Surg. 2013 Jan; 48(1):39-46.
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PubMed
subject areas
Angiogenesis Inhibitors
Animals
Antineoplastic Combined Chemotherapy Protocols
Cell Line, Tumor
Drug Administration Schedule
Drug Resistance, Neoplasm
Humans
Hypoxia-Inducible Factor 1, alpha Subunit
Indoles
Injections, Intraperitoneal
Mice
Mice, SCID
Neuroblastoma
Pyrroles
Reverse Transcriptase Polymerase Chain Reaction
Topoisomerase I Inhibitors
Topotecan
Treatment Outcome
Tumor Burden