Aph-1 interacts at the cell surface with proteins in the active gamma-secretase complex and membrane-tethered Notch.
Hansson EM, Strömberg K, Bergstedt S, Yu G, Näslund J, Lundkvist J, Lendahl U. Aph-1 interacts at the cell surface with proteins in the active gamma-secretase complex and membrane-tethered Notch. J Neurochem. 2005 Mar; 92(5):1010-20.