Harvard Catalyst Profiles

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Aph-1 interacts at the cell surface with proteins in the active gamma-secretase complex and membrane-tethered Notch.

Hansson EM, Strömberg K, Bergstedt S, Yu G, Näslund J, Lundkvist J, Lendahl U. Aph-1 interacts at the cell surface with proteins in the active gamma-secretase complex and membrane-tethered Notch. J Neurochem. 2005 Mar; 92(5):1010-20.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.