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A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.
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A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.
A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors. Proc Natl Acad Sci U S A. 2003 Nov 11; 100(23):13513-8.
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PubMed
subject areas
Animals
Anti-HIV Agents
Apoptosis
Benzylamines
Brain Neoplasms
Cell Division
Cell Line, Tumor
Chemokine CXCL12
Chemokines, CXC
Chemotaxis
Glioblastoma
Heterocyclic Compounds
Humans
In Situ Nick-End Labeling
Luciferases
Magnetic Resonance Imaging
Medulloblastoma
Mice
Mitogen-Activated Protein Kinase 1
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinases
Neoplasm Transplantation
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-akt
Receptors, CXCR4
Time Factors
authors with profiles
Jennifer Ang Chan, M.D.
Rosalind Anne Segal, M.D., Ph.D.
Andrew David Luster, M.D., Ph.D.