Harvard Catalyst Profiles

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Cathepsins L and Z are critical in degrading polyglutamine-containing proteins within lysosomes.

Bhutani N, Piccirillo R, Hourez R, Venkatraman P, Goldberg AL. Cathepsins L and Z are critical in degrading polyglutamine-containing proteins within lysosomes. J Biol Chem. 2012 May 18; 287(21):17471-82.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.