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Phenylpiperidine-type ?-secretase modulators target the transmembrane domain 1 of presenilin 1.
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Phenylpiperidine-type ?-secretase modulators target the transmembrane domain 1 of presenilin 1.
Phenylpiperidine-type ?-secretase modulators target the transmembrane domain 1 of presenilin 1. EMBO J. 2011 Oct 14; 30(23):4815-24.
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PubMed
subject areas
Allosteric Regulation
Alzheimer Disease
Amyloid beta-Peptides
Amyloid Precursor Protein Secretases
Animals
Binding Sites
CHO Cells
Cricetinae
Cricetulus
HEK293 Cells
Humans
Mice
Mice, Inbred C57BL
Peptide Fragments
Piperidines
Presenilin-1
Protein Binding
Protein Conformation
authors with profiles
Oksana Berezovska, Ph.D.