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Mutation-linked defective interdomain interactions within ryanodine receptor cause aberrant Ca²?release leading to catecholaminergic polymorphic ventricular tachycardia.

Suetomi T, Yano M, Uchinoumi H, Fukuda M, Hino A, Ono M, Xu X, Tateishi H, Okuda S, Doi M, Kobayashi S, Ikeda Y, Yamamoto T, Ikemoto N, Matsuzaki M. Mutation-linked defective interdomain interactions within ryanodine receptor cause aberrant Ca²?release leading to catecholaminergic polymorphic ventricular tachycardia. Circulation. 2011 Aug 09; 124(6):682-94.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.