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TACE is required for the activation of the EGFR by TGF-alpha in tumors.
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TACE is required for the activation of the EGFR by TGF-alpha in tumors.
Borrell-Pagès M, Rojo F, Albanell J, Baselga J, Arribas J. TACE is required for the activation of the EGFR by TGF-alpha in tumors. EMBO J. 2003 Mar 03; 22(5):1114-24.
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subject areas
ADAM Proteins
Amino Acid Sequence
Amyloid Precursor Protein Secretases
Animals
Aspartic Acid Endopeptidases
Breast Neoplasms
Carcinogenicity Tests
CHO Cells
Cricetinae
Culture Media, Conditioned
Endopeptidases
Female
HeLa Cells
Humans
Matrix Metalloproteinases, Membrane-Associated
Metalloendopeptidases
Mice
Mice, Nude
Neoplasms
Transforming Growth Factor alpha
Transplantation, Heterologous