Harvard Catalyst Profiles

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Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin.

Wieland Brown LC, Acker MG, Clardy J, Walsh CT, Fischbach MA. Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2549-53.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.