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Keith Dwain Crawford, Ph.D., M.D.

TitleInstructor in Orthopedic Surgery
InstitutionBrigham and Women's Hospital
DepartmentOrthopedic Surgery
AddressBrigham and Womens Hospital
Orthopaedics/Molecular Orthopaedics, BLI-152
221 Longwood Ave
Boston, MA 02115
Phone617/732-8607
Fax617/730-2846
Email
Other Positions
TitleFaculty Assistant Director
InstitutionHarvard Medical School
DepartmentDiversity Inclusion and Community Partnership
Mentoring - Completed Student Projects
Regulatory Mechanisms of Embryonic-like Adult Stem Cell
Summer, 6/9/2008 - 8/15/2008
Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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This graph shows the total number of publications by year, by first, middle/unknown, or last author.
  1. Crawford KW, Li C, Keung A, Su Z, Hughes MD, Greaves W, Kuritzkes D, Gulick R, Flexner C. Pharmacokinetic/pharmacodynamic modeling of the antiretroviral activity of the CCR5 antagonist Vicriviroc in treatment experienced HIV-infected subjects (ACTG protocol 5211). J Acquir Immune Defic Syndr. 2010 Apr; 53(5):598-605.
    View in: PubMed
  2. Fu S, Zhao H, Shi J, Abzhanov A, Crawford K, Ohno-Machado L, Zhou J, Du Y, Kuo WP, Zhang J, Jiang M, Jin JG. Peripheral arterial occlusive disease: global gene expression analyses suggest a major role for immune and inflammatory responses. BMC Genomics. 2008; 9:369.
    View in: PubMed
  3. Vasir B, Wu Z, Crawford K, Rosenblatt J, Zarwan C, Bissonnette A, Kufe D, Avigan D. Fusions of dendritic cells with breast carcinoma stimulate the expansion of regulatory T cells while concomitant exposure to IL-12, CpG oligodeoxynucleotides, and anti-CD3/CD28 promotes the expansion of activated tumor reactive cells. J Immunol. 2008 Jul 1; 181(1):808-21.
    View in: PubMed
  4. Winston Patrick Kuo1, Fang Liu, Eivind Hovig, Tor-Kristian Jensen, Keith Crawford, Lucila Ohno-Machado1 . A systematic comparison of gene expression measurements across different hybridization-based technologies. 2008.
  5. Keith D. Crawford and Chester A. Alper. Immune Response Genes and Infection. Genetic Susceptibility to Infectious Diseases. 2008.
  6. Vasir B, Wu Z, Crawford K, Rosenblatt J, Zarwan C, Bissonnette A, Kufe D and Avigan D. F. Fusions of Dendritic Cells with Breast Carcinoma Stimulate the Expansion of Regulatory T Cells while Concomitant Exposure to IL-12, CpG Oligodeoxynucleotides, and Anti-CD3/CD28 Promotes the Expansion of Activated Tumor Reactive Cells. Journal Immunology. 2008; 181:808-821.
  7. Keith D. Crawford. Stem Cells and Isolation Thereof. 2007.
  8. Crawford KD, Joo JJ, Fluckiger R, Vasir D, de Arce V, Evans CH, Thornhill TS . Identification of dendritic cells and CD133+ stem cells in the synovial fluid of osteoarthritic patients . Orhtopedic Research Society. 2007; Accepted.
  9. Vasir B, Avigan D, Wu Z, Crawford K, Turnquist S, Ren J, Kufe D. Dendritic cells induce MUC1 expression and polarization on human T cells by an IL-7-dependent mechanism. J Immunol. 2005 Feb 15; 174(4):2376-86.
    View in: PubMed
  10. Keith D. Crawford, Shawn Turnquist, Baldev Vasir, Rudolf Fluckiger, Katrine Cosmopolous, and Chester Alper . Dendritic Cells and Monocytes Differentially Secret Complement Protein C3 in Response to Various Stimuli . 2005.
  11. Crawford K. Immune Cell Biosensors and Methods using same. 2004.
  12. Turnquist, S., Smith, M., Crawford, K. The Effect of Sulfur-mustard on Primary Macrophages. Poster Presentation. 2004.
  13. Crawford, KD Alper CA . Selective activation of dendritic cell-based vaccines. 2004.
  14. Song E, Lee SK, Dykxhoorn DM, Novina C, Zhang D, Crawford K, Cerny J, Sharp PA, Lieberman J, Manjunath N, Shankar P. Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages. J Virol. 2003 Jul; 77(13):7174-81.
    View in: PubMed
  15. Crawford, KD Alper CA. Enrichment of dendritic cells from blood. 2003.
  16. Crawford K, Wang C, Kitchens B, Pantazopoulos V, Xu J, Gabuzda D, Reinherz E, Alper CA. CD2 ligation induces blood dendritic cell activation. FOCUS. 2003; 1, 3.
  17. Crawford K, Stark A, Kitchens B, Sternheim K, Pantazopoulos V, Triantafellow E, Wang Z, Vasir B, Larsen CE, Gabuzda D, Reinherz E, Alper CA. CD2 engagement induces dendritic cell activation: implications for immune surveillance and T-cell activation. Blood. 2003 Sep 1; 102(5):1745-52.
    View in: PubMed
  18. Smith MG, Stone W, Crawford K, Ward P, Till G, Das S. . Are Antioxidant Liposomes (STIMAL) The Universal Antidote to Several Weapons of Mass Destruction?. Jane’s Online. 2003.
  19. Crawford KD, Wang C, Kitchens B, Pantazopoulos V, Xu J, Gabuzda D, Reinherz E, Alper CA . CD2 engagement induces dendritic cell activation: implications for immune surveillance and T cell activation. 2003.
  20. Wang J, Crawford K, Yuan M, Wang H, Gorry PR, Gabuzda D. Regulation of CC chemokine receptor 5 and CD4 expression and human immunodeficiency virus type 1 replication in human macrophages and microglia by T helper type 2 cytokines. J Infect Dis. 2002 Apr 1; 185(7):885-97.
    View in: PubMed
  21. Turnquist S, Crawford KD . N-acetylcysteine prevents CEES induced apoptosis: implications for possible antidote for chemical and biological weapons. Proceedings of Chemical Weapons Defense Institute, Aberdeen Providing Grounds. 2002.
  22. Gorry PR, Bristol G, Zack JA, Ritola K, Swanstrom R, Birch CJ, Bell JE, Bannert N, Crawford K, Wang H, Schols D, De Clercq E, Kunstman K, Wolinsky SM, Gabuzda D. Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity. J Virol. 2001 Nov; 75(21):10073-89.
    View in: PubMed
  23. Crawford KD Alper CA . Enrichment of dendritic cells from blood. 2001.
  24. Uko GP, Fraser PA, Awdeh ZL, Fici DA, Crawford KD, Larsen CE, Alper CA. Hepatitis B surface antigen- and tetanus toxoid-specific clonal expansion of CD4+ cells in vitro determined by TCRBV CDR3 length and nucleotide sequence. Genes Immun. 2001 Feb; 2(1):11-9.
    View in: PubMed
  25. Crawford K, Alper CA. Genetics of the complement system. Rev Immunogenet. 2000; 2(3):323-38.
    View in: PubMed
  26. Crawford K. CEES induces cellular apoptosis via the caspase pathways: implications for the development of effective countermeasures. Proceedings of the Mustard Consortium. 2000.
  27. Crawford K, Gabuzda D, Pantazopoulos V, Xu J, Clement C, Reinherz E, Alper CA. Circulating CD2+ monocytes are dendritic cells. J Immunol. 1999 Dec 1; 163(11):5920-8.
    View in: PubMed
  28. Crawford K, Wang C, Kitchens B, Gabuzda D, Reinherz E, Alper A. CD2-induced activation of human blood dendritic cell precursors. FASEB J. 1998; 12:A300.
  29. Alper C, Clement C, Gabuzda D, Reinherz E, Crawford K. CD2 distinguishes human blood dendritic cell precursors from monocytes. FASEB J. 1998; 12:A275.
  30. Crawford K, Alper C, Shi B, Vasir B, Gabuzda D . A subpopulation of immature blood dendritic cells is highly susceptible to infection by macrophage-tropic HIV-1. Proceedings 9th Meeting of the National Cooperative Vaccine Development Groups for AIDS. 1997.
  31. Crawford KD. Human peripheral blood dendritic cells: phenotype, morphology, and function. 1997.
  32. Crawford K, Alper C, Shi B, Vasir B, Gabuzda D . A subpopulation of immature blood dendritic cells is highly susceptible to infection by macrophage-tropic HIV-1. Proceedings 4th Conference on Retroviruses and Opportunistic Infectionsroceedings. 1997.
  33. Gabuzda DH, Li H, Lawrence K, Vasir BS, Crawford K, Langhoff E. Essential role of vif in establishing productive HIV-1 infection in peripheral blood T lymphocytes and monocyte/macrophages. J Acquir Immune Defic Syndr. 1994 Sep; 7(9):908-15.
    View in: PubMed
  34. Crawford K, Alper, C Tedder T. Circulating human blood dendritic cells express the HB-15 surface antigen (CD83), which is not detected on other blood leukocytes. Proceedings 34th Annual Meeting American Society of Hematology. 1992.
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