Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution
More Search Options
Menu
History
See all (10) pages
Back to Dennis Poe

Martha Murray, M.D.

TitleAssociate Professor of Orthopedic Surgery
InstitutionChildren's Hospital Boston
DepartmentOrthopedic Surgery
AddressChildrens Hospital
Orthopaedics, Hunnewell 2
300 Longwood Ave
Boston, MA 02115
Phone617/355-6617
Fax617/730-0459
Email
Mentoring - Current Student Opportunities
ACL Research Assistant  [login at prompt]
Available: 10/12/2011, Expires: 6/15/2012
This position involves assisting with the histologic analysis of ACLs treated with a novel treatment method, enhanced primary repair. The student would assist with the processing of the specimens, performing histology and immunohistochemistry, and analysing the results. In addition, the student would be exposed to other projects in the lab, including cell culture, biochemistry and biomechanical assays. This is a basic science research opportunity in Orthopaedic Surgery, it does not involve clinical experience or shadowing opportunities. This can be done as a part-time opportunity, authorship on any ensuing publication would be predicated on the percentage of the project completed by the student.
Mentoring - Completed Student Projects
A Histologic Study of Enhanced ACL Repair
Summer, 6/2/2008 - 8/29/2008
Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All  |  Timeline
List All  |  Timeline
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
  1. Fleming BC, Vajapeyam S, Connolly SA, Magarian EM, Murray MM. The use of magnetic resonance imaging to predict ACL graft structural properties. J Biomech. 2011 Nov 10; 44(16):2843-6.
    View in: PubMed
  2. Vavken P, Sadoghi P, Murray MM. The effect of platelet concentrates on graft maturation and graft-bone interface healing in anterior cruciate ligament reconstruction in human patients: a systematic review of controlled trials. Arthroscopy. 2011 Nov; 27(11):1573-83.
    View in: PubMed
  3. Cheng M, Johnson VM, Murray MM. Effects of age and platelet-rich plasma on ACL cell viability and collagen gene expression. J Orthop Res. 2012 Jan; 30(1):79-85.
    View in: PubMed
  4. Haus BM, Mastrangelo AN, Murray MM. Effect of anterior cruciate healing on the uninjured ligament insertion site. J Orthop Res. 2012 Jan; 30(1):86-94.
    View in: PubMed
  5. Vavken P, Murray MM. Treating anterior cruciate ligament tears in skeletally immature patients. Arthroscopy. 2011 May; 27(5):704-16.
    View in: PubMed
  6. Harrison SL, Vavken P, Murray MM. Erythrocytes inhibit ligament fibroblast proliferation in a collagen scaffold. J Orthop Res. 2011 Sep; 29(9):1361-6.
    View in: PubMed
  7. Harrison S, Vavken P, Kevy S, Jacobson M, Zurakowski D, Murray MM. Platelet activation by collagen provides sustained release of anabolic cytokines. Am J Sports Med. 2011 Apr; 39(4):729-34.
    View in: PubMed
  8. Steinert AF, Kunz M, Prager P, Barthel T, Jakob F, Nöth U, Murray MM, Evans CH, Porter RM. Mesenchymal stem cell characteristics of human anterior cruciate ligament outgrowth cells. Tissue Eng Part A. 2011 May; 17(9-10):1375-88.
    View in: PubMed
  9. Vavken P, Murray MM. The potential for primary repair of the ACL. Sports Med Arthrosc. 2011 Mar; 19(1):44-9.
    View in: PubMed
  10. Vavken P, Saad FA, Fleming BC, Murray MM. VEGF receptor mRNA expression by ACL fibroblasts is associated with functional healing of the ACL. Knee Surg Sports Traumatol Arthrosc. 2011 Oct; 19(10):1675-82.
    View in: PubMed
  11. Mastrangelo AN, Vavken P, Fleming BC, Harrison SL, Murray MM. Reduced platelet concentration does not harm PRP effectiveness for ACL repair in a porcine in vivo model. J Orthop Res. 2011 Jul; 29(7):1002-7.
    View in: PubMed
  12. Magarian EM, Fleming BC, Harrison SL, Mastrangelo AN, Badger GJ, Murray MM. Delay of 2 or 6 weeks adversely affects the functional outcome of augmented primary repair of the porcine anterior cruciate ligament. Am J Sports Med. 2010 Dec; 38(12):2528-34.
    View in: PubMed
  13. Murray MM, Magarian EM, Harrison SL, Mastrangelo AN, Zurakowski D, Fleming BC. The effect of skeletal maturity on functional healing of the anterior cruciate ligament. J Bone Joint Surg Am. 2010 Sep 1; 92(11):2039-49.
    View in: PubMed
  14. Magarian EM, Vavken P, Murray MM. Human anterior cruciate ligament fibroblasts from immature patients have a stronger in vitro response to platelet concentrates than those from mature individuals. Knee. 2011 Aug; 18(4):247-51.
    View in: PubMed
  15. Mastrangelo AN, Haus BM, Vavken P, Palmer MP, Machan JT, Murray MM. Immature animals have higher cellular density in the healing anterior cruciate ligament than adolescent or adult animals. J Orthop Res. 2010 Aug; 28(8):1100-6.
    View in: PubMed
  16. Vavken P, Saad FA, Murray MM. Age dependence of expression of growth factor receptors in porcine ACL fibroblasts. J Orthop Res. 2010 Aug; 28(8):1107-12.
    View in: PubMed
  17. Haddad-Weber M, Prager P, Kunz M, Seefried L, Jakob F, Murray MM, Evans CH, Nöth U, Steinert AF. BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells. Cytotherapy. 2010 Jul; 12(4):505-13.
    View in: PubMed
  18. Murray MM, Magarian E, Zurakowski D, Fleming BC. Bone-to-bone fixation enhances functional healing of the porcine anterior cruciate ligament using a collagen-platelet composite. Arthroscopy. 2010 Sep; 26(9 Suppl):S49-57.
    View in: PubMed
  19. Fleming BC, Magarian EM, Harrison SL, Paller DJ, Murray MM. Collagen scaffold supplementation does not improve the functional properties of the repaired anterior cruciate ligament. J Orthop Res. 2010 Jun; 28(6):703-9.
    View in: PubMed
  20. Cheng M, Wang H, Yoshida R, Murray MM. Platelets and plasma proteins are both required to stimulate collagen gene expression by anterior cruciate ligament cells in three-dimensional culture. Tissue Eng Part A. 2010 May; 16(5):1479-89.
    View in: PubMed
  21. Mastrangelo AN, Magarian EM, Palmer MP, Vavken P, Murray MM. The effect of skeletal maturity on the regenerative function of intrinsic ACL cells. J Orthop Res. 2010 May; 28(5):644-51.
    View in: PubMed
  22. Abreu EL, Palmer MP, Murray MM. Collagen density significantly affects the functional properties of an engineered provisional scaffold. J Biomed Mater Res A. 2010 Apr; 93(1):150-7.
    View in: PubMed
  23. Vavken P, Murray MM. Translational studies in anterior cruciate ligament repair. Tissue Eng Part B Rev. 2010 Feb; 16(1):5-11.
    View in: PubMed
  24. Vavken P, Joshi SM, Murray MM. Fibrin concentration affects ACL fibroblast proliferation and collagen synthesis. Knee. 2011 Jan; 18(1):42-6.
    View in: PubMed
  25. Kritsaneepaiboon S, Shah R, Murray MM, Kleinman PK. Posterior periosteal disruption in Salter-Harris Type II fractures of the distal femur: evidence for a hyperextension mechanism. AJR Am J Roentgenol. 2009 Dec; 193(6):W540-5.
    View in: PubMed
  26. Joshi SM, Mastrangelo AN, Magarian EM, Fleming BC, Murray MM. Collagen-platelet composite enhances biomechanical and histologic healing of the porcine anterior cruciate ligament. Am J Sports Med. 2009 Dec; 37(12):2401-10.
    View in: PubMed
  27. Vavken P, Joshi S, Murray MM. TRITON-X is most effective among three decellularization agents for ACL tissue engineering. J Orthop Res. 2009 Dec; 27(12):1612-8.
    View in: PubMed
  28. Murray MM, Palmer M, Abreu E, Spindler KP, Zurakowski D, Fleming BC. Platelet-rich plasma alone is not sufficient to enhance suture repair of the ACL in skeletally immature animals: an in vivo study. J Orthop Res. 2009 May; 27(5):639-45.
    View in: PubMed
  29. Spindler KP, Murray MM, Carey JL, Zurakowski D, Fleming BC. The use of platelets to affect functional healing of an anterior cruciate ligament (ACL) autograft in a caprine ACL reconstruction model. J Orthop Res. 2009 May; 27(5):631-8.
    View in: PubMed
  30. Pearse RV, Esshaki D, Tabin CJ, Murray MM. Genome-wide expression analysis of intra- and extraarticular connective tissue. J Orthop Res. 2009 Apr; 27(4):427-34.
    View in: PubMed
  31. Fleming BC, Spindler KP, Palmer MP, Magarian EM, Murray MM. Collagen-platelet composites improve the biomechanical properties of healing anterior cruciate ligament grafts in a porcine model. Am J Sports Med. 2009 Aug; 37(8):1554-63.
    View in: PubMed
  32. Murray MM. Current status and potential of primary ACL repair. Clin Sports Med. 2009 Jan; 28(1):51-61.
    View in: PubMed
  33. Fleming BC, Carey JL, Spindler KP, Murray MM. Can suture repair of ACL transection restore normal anteroposterior laxity of the knee? An ex vivo study. J Orthop Res. 2008 Nov; 26(11):1500-5.
    View in: PubMed
  34. Jacobson M, Fufa D, Abreu EL, Kevy S, Murray MM. Platelets, but not erythrocytes, significantly affect cytokine release and scaffold contraction in a provisional scaffold model. Wound Repair Regen. 2008 May-Jun; 16(3):370-8.
    View in: PubMed
  35. Fufa D, Shealy B, Jacobson M, Kevy S, Murray MM. Activation of platelet-rich plasma using soluble type I collagen. J Oral Maxillofac Surg. 2008 Apr; 66(4):684-90.
    View in: PubMed
  36. Steiner ME, Murray MM, Rodeo SA. Strategies to improve anterior cruciate ligament healing and graft placement. Am J Sports Med. 2008 Jan; 36(1):176-89.
    View in: PubMed
  37. Steinert AF, Weber M, Kunz M, Palmer GD, Nöth U, Evans CH, Murray MM. In situ IGF-1 gene delivery to cells emerging from the injured anterior cruciate ligament. Biomaterials. 2008 Mar; 29(7):904-16.
    View in: PubMed
  38. Murray, M. M., Mankin, H. J., Glowacki, J. The Musculoskeletal System. O’Leary, JP editor. The Physiologic Basis of Surgery. 2007.
  39. Murray MM, Spindler KP, Ballard P, Welch TP, Zurakowski D, Nanney LB. Enhanced histologic repair in a central wound in the anterior cruciate ligament with a collagen-platelet-rich plasma scaffold. J Orthop Res. 2007 Aug; 25(8):1007-17.
    View in: PubMed
  40. Kocher MS, Kasser JR, Waters PM, Bae D, Snyder BD, Hresko MT, Hedequist D, Karlin L, Kim YJ, Murray MM, Millis MB, Emans JB, Dichtel L, Matheney T, Lee BM. Lateral entry compared with medial and lateral entry pin fixation for completely displaced supracondylar humeral fractures in children. A randomized clinical trial. J Bone Joint Surg Am. 2007 Apr; 89(4):706-12.
    View in: PubMed
  41. Murray MM, Spindler KP, Abreu E, Muller JA, Nedder A, Kelly M, Frino J, Zurakowski D, Valenza M, Snyder BD, Connolly SA. Collagen-platelet rich plasma hydrogel enhances primary repair of the porcine anterior cruciate ligament. J Orthop Res. 2007 Jan; 25(1):81-91.
    View in: PubMed
  42. Duretti Fufa, MD; Blake Shealy; May Jacobson, PhD; Sherwin Kevy, MD; Martha Meaney Murray, MD. Activation of Platelet-Rich Plasma Using Soluble Type I Collagen. Journal of Oral and Maxillofacial Surgery, accepted for publication. 2007.
  43. Abreu E., Marler J., Murray MM. The Effect of Collagen Concentration on Platelet-Rich Plasma Hydrogels. 2007.
  44. Murray MM., Spindler KP., Abreu E., Muller J., Nedder A., Kelly M., Frino J., Zurakowski D., Valenza M., Snyder BD., Palmer M., Connolly S. Collagen-Platelet Rich Plasma Hydrogel Enhances Primary Repair of the Porcine Anterior Cruciate Ligament. 2007.
  45. Murray MM., Spindler KP., Ballard P., Welch T., Nanney LB. Histologic Differences in Healing of Intra-Articular and Extra-Articular Ligament Wounds. 2007.
  46. Murray MM., Spindler KP., Ballard P., Welch T., Nanney LB. Enhanced Histologic Repair in a Central Defect in the Anterior Cruciate Ligament with a Collagen-Platelet Rich Plasma Scaffold. 2007.
  47. Fufa D., Shealy B., Jacobson M., Kevy S., Murray MM. Type I Collagen as a Platelet Activator in Platelet-Rich Plasma Hydrogels. 2007.
  48. Murray, MM., Spindler, K.P., Ballard, P., Welch, T., Nanney, LB. Enhanced Histologic Repair in a Central Defect in the ACL with a Collagen-PRP Scaffold. J Orthop Res. 2007; 25(8):1007-1017.
  49. Yeh J., Shealy B., Jacobson M., Sherwin K., Hootnik J., Murray MM. . Effect of Collagen Source on Human ACL Cell Proliferation and Platelet Activation. 2007.
  50. Mahan ST, Murray MM, Woolf AD, Kasser JR. Increased blood lead levels in an adolescent girl from a retained bullet. A case report. J Bone Joint Surg Am. 2006 Dec; 88(12):2726-9.
    View in: PubMed
  51. Mesiha M, Zurakowski D, Soriano J, Nielson JH, Zarins B, Murray MM. Pathologic characteristics of the torn human meniscus. Am J Sports Med. 2007 Jan; 35(1):103-12.
    View in: PubMed
  52. Murray MM, Spindler KP, Devin C, Snyder BS, Muller J, Takahashi M, Ballard P, Nanney LB, Zurakowski D. Use of a collagen-platelet rich plasma scaffold to stimulate healing of a central defect in the canine ACL. J Orthop Res. 2006 Apr; 24(4):820-30.
    View in: PubMed
  53. Murray MM, Forsythe B, Chen F, Lee SJ, Yoo JJ, Atala A, Steinert A. The effect of thrombin on ACL fibroblast interactions with collagen hydrogels. J Orthop Res. 2006 Mar; 24(3):508-15.
    View in: PubMed
  54. Spindler KP, Murray MM, Devin C, Nanney LB, Davidson JM. The central ACL defect as a model for failure of intra-articular healing. J Orthop Res. 2006 Mar; 24(3):401-6.
    View in: PubMed
  55. Murray, M. M., Murray, MF. Biology and Gene-Based Therapy. The Pediatric and Adolescent Knee, Micheli, LJ and Kocher, MS, eds. 2006.
  56. Steinert A., Karl N., Pilapil C., Noth U., Evans CH., Murray, M.M. Multilineage Mesenchymal Differentiation Potential of Cells Migrating out of the Anterior Cruciate Ligament. 2006.
  57. Murray, MM, Spindler, KP, Zurakowski, DA, Connolly, SA. Enhancement of suture repair of the ACL using a collagen-PRP hydrogel. 2006.
  58. Murrat, MM inventor. Methods and Procedures for Ligament Repair,. 2006.
  59. Murray MM., Murray MF., Marler JM., Spindler KP., Sawyer AJ., inventors. Biologic Replacement for Fibrin Clot. 2005.
  60. Murray MM., Slocum A., Want YC., Walker D., Carvey M., Salameni A., inventors. Delivery Device for Tissue Repair. 2005.
  61. Murray, MM, Spindler, KP. Anterior Cruciate Ligament Healing and Primary Repair. Sports Medicine and Arthroscopy Review. 2005; 13(3):151-155.
  62. Murray, M.M., Steinert, A., Evans, C., Pilapil, C., Palmer, G., Betz, O. In Situ IGF-1 Gene Transfer Enhances Healing Response in the Anterior Cruciate Ligament. 2005.
  63. Murray, MM., Spindler, KP. Anterior Cruciate Ligament Healing and Primary Repair. 2005; 13(3):151-156.
  64. Fufa, D., Chen, F. and Murray, M.M. . The Effect of Insoluble Collagen Morphology on Fibroblast Migration, Proliferation and Collagen Production. 2005.
  65. Pascher A, Steinert AF, Palmer GD, Betz O, Gouze JN, Gouze E, Pilapil C, Ghivizzani SC, Evans CH, Murray MM. Enhanced repair of the anterior cruciate ligament by in situ gene transfer: evaluation in an in vitro model. Mol Ther. 2004 Aug; 10(2):327-36.
    View in: PubMed
  66. Murray MM, Weiler A, Spindler KP. Interspecies variation in the fibroblast distribution of the anterior cruciate ligament. Am J Sports Med. 2004 Sep; 32(6):1484-91.
    View in: PubMed
  67. Kolker D, Murray M, Wilson M. Osteochondral defects of the talus treated with autologous bone grafting. J Bone Joint Surg Br. 2004 May; 86(4):521-6.
    View in: PubMed
  68. Murray MM, Zurakowski D, Vrahas MS. The death of articular chondrocytes after intra-articular fracture in humans. J Trauma. 2004 Jan; 56(1):128-31.
    View in: PubMed
  69. Steinert, A., Palmer, G., Betz, O., Gouze, I., Gouze, JM., Pilapil, C., Ghivizzani, S., Evans, C., Murray, M.M. In Situ IGF-1 Gene Transfer for Enhancing Healing of the ACL – Evaluation in an in vitro model. Basic Science Poster Prize. 2004.
  70. Steinert, AF., Chen, F., Evans, CH., Murray, MM. Novel Biological Approaches to Enhance Primary Repair of the Anterior Cruciate Ligament. 2004; 81-83.
  71. Murray MM., Murray MF., Marler JM., Spindler KP., Sawyer AJ., inventors. Biologic Replacement for Fibrin Clot. 2003.
  72. Spindler KP, Murray MM, Detwiler KB, Tarter JT, Dawson JM, Nanney LB, Davidson JM. The biomechanical response to doses of TGF-beta 2 in the healing rabbit medial collateral ligament. J Orthop Res. 2003 Mar; 21(2):245-9.
    View in: PubMed
  73. Murray, MM., Bernstein, J. Ligaments. Musculoskeletal Medicine, Berstein J, editor. 2003.
  74. Murray, MM, Rice, K, Wright, RJ, Spector, M. The Effect of selected growth factors on human anterior cruciate ligament cell interactions with a three dimensional collagen-GAG scaffold. J Orthop Res. 2003; 21:238-244.
  75. Murray, M.M., section editor for Basic Science. Musculoskeletal Medicine. Bernstein, J. Senior Editor. 2003.
  76. Murray, MM., Berstein, J. Meniscus. Musculoskeletal Medicine, Bernstein J, editor. 2003.
  77. Murray MM, Bennett R, Zhang X, Spector M. Cell outgrowth from the human ACL in vitro: regional variation and response to TGF-beta1. J Orthop Res. 2002 Jul; 20(4):875-80.
    View in: PubMed
  78. Murray, MM., Mankin, HJ., Glowacki, J. The Musculoskeletal System. The Physiologic Basis of Surgery, O'Leary JP, editor. 2002.
  79. Murray, M. M., Rice, K. R., Spector, M. S.,. The effects of selected crosslinking protocols on human ACL cell interactions with 3-D collagen-GAG scaffolds. 2002.
  80. Murray, M. M., Sawyer, A., Zurakowski, D., Gerbino, P., Micheli, L. . The effect of age on the response to injury in the human ACL. 2002.
  81. Murray, M. M., Martin, S. D., Spector, M. . Changes in cell number density and smooth muscle actin expression after rupture of the human rotator cuff tendon. 2002.
  82. Murray MM, Spector M. The migration of cells from the ruptured human anterior cruciate ligament into collagen-glycosaminoglycan regeneration templates in vitro. Biomaterials. 2001 Sep; 22(17):2393-402.
    View in: PubMed
  83. Murray, MM., Murray, MF., Marler JM., inventors. Biologic Replacement for Fibrin Clot. 2001.
  84. Ahluwalia S, Fehm M, Murray MM, Martin SD, Spector M. Distribution of smooth muscle actin-containing cells in the human meniscus. J Orthop Res. 2001 Jul; 19(4):659-64.
    View in: PubMed
  85. Premdas J, Tang JB, Warner JP, Murray MM, Spector M. The presence of smooth muscle actin in fibroblasts in the torn human rotator cuff. J Orthop Res. 2001 Mar; 19(2):221-8.
    View in: PubMed
  86. Murray, MM., invited editorial. Effect of the intra-articular environment on healing of the ruptured anterior cruciate ligament. 2001.
  87. Murray, M. M., Dawson, C., Kocolas, I., Spector, M. . Gender differences in the histology of the human anterior cruciate ligament. 2001.
  88. Murray MM, Martin SD, Martin TL, Spector M. Histological changes in the human anterior cruciate ligament after rupture. J Bone Joint Surg Am. 2000 Oct; 82-A(10):1387-97.
    View in: PubMed
  89. Murray MM, Martin SD, Spector M. Migration of cells from human anterior cruciate ligament explants into collagen-glycosaminoglycan scaffolds. J Orthop Res. 2000 Jul; 18(4):557-64.
    View in: PubMed
  90. Murray, MM., inventor. Biologic Replacement for Fibrin Clot for Intra-articular Use. 2000.
  91. Qiu, W, Murray, MM, Shortkroff, S, Lee, CR, Martin, SD, Spector, M. Outgrowth of Chondrocytes from human articular cartilage explants and expression of alpha-smooth muscle actin. Would Repair and Regeneration. 2000; 18:383-391.
  92. Murray, MM., inventor. Biologic Replacement for Fibrin Clot for Intra-articular Use, Provisional application. 1999.
  93. Murray, M.M. E.R. Ortho, Resident Handbook, Harvard Combined Orthopaedic Residency Program. 1999.
  94. Murray MM, Spector M. Fibroblast distribution in the anteromedial bundle of the human anterior cruciate ligament: the presence of alpha-smooth muscle actin-positive cells. J Orthop Res. 1999 Jan; 17(1):18-27.
    View in: PubMed
  95. Murray, M.M. Guided Tissue Regeneration of the ACL: Preliminary Studies. 1999.
  96. Murray, M.M. E.R. Ortho, Resident Handbook, Harvard Combined Orthopaedic Residency Program. 1998.
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
Murray's Networks
Click the "see all" links for more information and interactive visualizations!
Concepts
Derived automatically from this person's publications.
See all (199) concepts
Co-Authors
People in Profiles who have published with this person.
See all (33) people
Similar People
People who share similar concepts with this person.
See all (60) people
Same Department
People who are also in this person's primary department.
See all (66) people
Physical Neighbors
People whose addresses are nearby this person.