Levy, Dan
eCommons Login: DL4
first name: Dan
last name: Levy
coauthor of: Strassman, Andrew
coauthor of: Burstein, Rami
coauthor of: Moskowitz, Michael
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full name: Dan Levy, Ph.D.
has faculty rank: Associate Professor
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Authorship 108212
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Local nitric oxide synthase activity in a model of neuropathic pain.

Terminating migraine with allodynia and ongoing central sensitization using parenteral administration of COX1/COX2 inhibitors.
PubMed Identifier: 15985101
author list: Jakubowski M, Levy D, Goor-Aryeh I, Collins B, Bajwa Z, Burstein R
published in: Headache
information resource reference: Terminating migraine with allodynia and ongoing central sensitization using parenteral administration of COX1/COX2 inhibitors. Headache. 2005 Jul-Aug; 45(7):850-61.
journal title abbreviation: Headache
publication date: 2005-07-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1070580
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Dissociation between CSD-Evoked Metabolic Perturbations and Meningeal Afferent Activation and Sensitization: Implications for Mechanisms of Migraine Headache Onset.

Authorship 1070581
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: The CGRP receptor antagonist BIBN4096 inhibits prolonged meningeal afferent activation evoked by brief local K+ stimulation but not cortical spreading depression-induced afferent sensitization.

Authorship 1070582
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Cortical Spreading Depression Promotes Persistent Mechanical Sensitization of Intracranial Meningeal Afferents: Implications for the Intracranial Mechanosensitivity of Migraine.

Authorship 1070583
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author rank in publication: 2
linked author: Levy, Dan
linked information resource: Development of CGRP-dependent pain and headache related behaviours in a rat model of concussion: Implications for mechanisms of post-traumatic headache.

Authorship 1070584
type: Authorship
author rank in publication: 5
linked author: Levy, Dan
linked information resource: Cranial dural permeability of inflammatory nociceptive mediators: Potential implications for animal models of migraine.

Authorship 1070585
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Modulation of intracranial meningeal nociceptor activity by cortical spreading depression: a reassessment.

Authorship 1070586
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linked author: Levy, Dan
linked information resource: Experimental evidence for weaker endogenous inhibition of trigeminal pain than extra-trigeminal pain in healthy individuals.

Experimental evidence for weaker endogenous inhibition of trigeminal pain than extra-trigeminal pain in healthy individuals.
PubMed Identifier: 28990805
author list: Levy D, Abdian L, Dekel-Steinkeller M, Defrin R
published in: Cephalalgia : an international journal of headache
information resource reference: Experimental evidence for weaker endogenous inhibition of trigeminal pain than extra-trigeminal pain in healthy individuals. Cephalalgia. 2018 06; 38(7):1307-1315.
journal title abbreviation: Cephalalgia
publication date: 2017-10-09T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Modulation of intracranial meningeal nociceptor activity by cortical spreading depression: a reassessment.
PubMed Identifier: 25695654
author list: Zhao J, Levy D
published in: Journal of neurophysiology
information resource reference: Modulation of intracranial meningeal nociceptor activity by cortical spreading depression: a reassessment. J Neurophysiol. 2015 Apr 01; 113(7):2778-85.
journal title abbreviation: J Neurophysiol
publication date: 2015-02-18T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Dissociation between CSD-Evoked Metabolic Perturbations and Meningeal Afferent Activation and Sensitization: Implications for Mechanisms of Migraine Headache Onset.
PubMed Identifier: 29703787
author list: Zhao J, Levy D
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Dissociation between CSD-Evoked Metabolic Perturbations and Meningeal Afferent Activation and Sensitization: Implications for Mechanisms of Migraine Headache Onset. J Neurosci. 2018 05 30; 38(22):5053-5066.
journal title abbreviation: J Neurosci
publication date: 2018-04-27T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

The CGRP receptor antagonist BIBN4096 inhibits prolonged meningeal afferent activation evoked by brief local K+ stimulation but not cortical spreading depression-induced afferent sensitization.
PubMed Identifier: 29430561
author list: Zhao J, Levy D
published in: Pain reports
information resource reference: The CGRP receptor antagonist BIBN4096 inhibits prolonged meningeal afferent activation evoked by brief local K+ stimulation but not cortical spreading depression-induced afferent sensitization. Pain Rep. 2018 Jan; 3(1):e632.
journal title abbreviation: Pain Rep
publication date: 2017-12-05T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Cortical Spreading Depression Promotes Persistent Mechanical Sensitization of Intracranial Meningeal Afferents: Implications for the Intracranial Mechanosensitivity of Migraine.
PubMed Identifier: 28127585
author list: Zhao J, Levy D
published in: eNeuro
information resource reference: Cortical Spreading Depression Promotes Persistent Mechanical Sensitization of Intracranial Meningeal Afferents: Implications for the Intracranial Mechanosensitivity of Migraine. eNeuro. 2016 Nov-Dec; 3(6).
journal title abbreviation: eNeuro
publication date: 2016-12-22T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Modulation of meningeal nociceptors mechanosensitivity by peripheral proteinase-activated receptor-2: the role of mast cells.
PubMed Identifier: 18254896
author list: Zhang XC, Levy D
published in: Cephalalgia : an international journal of headache
information resource reference: Modulation of meningeal nociceptors mechanosensitivity by peripheral proteinase-activated receptor-2: the role of mast cells. Cephalalgia. 2008 Mar; 28(3):276-84.
journal title abbreviation: Cephalalgia
publication date: 2008-03-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Delayed peripheral nerve degeneration, regeneration, and pain in mice lacking inducible nitric oxide synthase.
PubMed Identifier: 11379816
author list: Levy D, Kubes P, Zochodne DW
published in: Journal of neuropathology and experimental neurology
information resource reference: Delayed peripheral nerve degeneration, regeneration, and pain in mice lacking inducible nitric oxide synthase. J Neuropathol Exp Neurol. 2001 May; 60(5):411-21.
journal title abbreviation: J Neuropathol Exp Neurol
publication date: 2001-05-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Nitric oxide in damage, disease and repair of the peripheral nervous system.
PubMed Identifier: 16191393
author list: Zochodne DW, Levy D
published in: Cellular and molecular biology (Noisy-le-Grand, France)
information resource reference: Nitric oxide in damage, disease and repair of the peripheral nervous system. Cell Mol Biol (Noisy-le-grand). 2005 Sep 05; 51(3):255-67.
journal title abbreviation: Cell Mol Biol (Noisy-le-grand)
publication date: 2005-09-05T00:00:00
year: 2005
type: Academic Article
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Activation of meningeal nociceptors by cortical spreading depression: implications for migraine with aura.
PubMed Identifier: 20592202
author list: Zhang X, Levy D, Noseda R, Kainz V, Jakubowski M, Burstein R
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Activation of meningeal nociceptors by cortical spreading depression: implications for migraine with aura. J Neurosci. 2010 Jun 30; 30(26):8807-14.
journal title abbreviation: J Neurosci
publication date: 2010-06-30T00:00:00
year: 2010
type: Academic Article
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Authorship 1083294
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linked author: Levy, Dan
linked information resource: Current understanding of meningeal and cerebral vascular function underlying migraine headache.

Current understanding of meningeal and cerebral vascular function underlying migraine headache.
PubMed Identifier: 29929378
author list: Levy D, Labastida-Ramirez A, MaassenVanDenBrink A
published in: Cephalalgia : an international journal of headache
information resource reference: Current understanding of meningeal and cerebral vascular function underlying migraine headache. Cephalalgia. 2019 11; 39(13):1606-1622.
journal title abbreviation: Cephalalgia
publication date: 2018-06-21T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
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Mast cell involvement in the pathophysiology of migraine headache: A hypothesis.
PubMed Identifier: 16927959
author list: Levy D, Burstein R, Strassman AM
published in: Headache
information resource reference: Mast cell involvement in the pathophysiology of migraine headache: A hypothesis. Headache. 2006 Jun; 46 Suppl 1:S13-8.
journal title abbreviation: Headache
publication date: 2006-06-01T00:00:00
year: 2006
type: Academic Article
type: Article
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type: Information Resource

Strides Toward Better Understanding of Post-Traumatic Headache Pathophysiology Using Animal Models.
PubMed Identifier: 30073545
author list: Bree D, Levy D
published in: Current pain and headache reports
information resource reference: Strides Toward Better Understanding of Post-Traumatic Headache Pathophysiology Using Animal Models. Curr Pain Headache Rep. 2018 Aug 02; 22(10):67.
journal title abbreviation: Curr Pain Headache Rep
publication date: 2018-08-02T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Migraine pain and nociceptor activation--where do we stand?
PubMed Identifier: 20546325
author list: Levy D
published in: Headache
information resource reference: Migraine pain and nociceptor activation--where do we stand? Headache. 2010 May; 50(5):909-16.
journal title abbreviation: Headache
publication date: 2010-05-01T00:00:00
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Principal Investigator
type: Researcher Role
researcher role of: Levy, Dan
contributes to: MECHANISMS OF CSD-EVOKED PERSISTENT ACTIVATION OF MENINGEAL NOCICEPTORS

MECHANISMS OF CSD-EVOKED PERSISTENT ACTIVATION OF MENINGEAL NOCICEPTORS
end date: 2023-05-31
principal investigator name: Dan Levy
start date: 2018-09-01
type: Grant
sponsor award id: 2R01NS078263-05

Migraine pain, meningeal inflammation, and mast cells.
PubMed Identifier: 19457286
author list: Levy D
published in: Current pain and headache reports
information resource reference: Migraine pain, meningeal inflammation, and mast cells. Curr Pain Headache Rep. 2009 Jun; 13(3):237-40.
journal title abbreviation: Curr Pain Headache Rep
publication date: 2009-06-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Tumor necrosis factor-a induces sensitization of meningeal nociceptors mediated via local COX and p38 MAP kinase actions.
PubMed Identifier: 21036476
author list: Zhang XC, Kainz V, Burstein R, Levy D
published in: Pain
information resource reference: Tumor necrosis factor-a induces sensitization of meningeal nociceptors mediated via local COX and p38 MAP kinase actions. Pain. 2011 Jan; 152(1):140-149.
journal title abbreviation: Pain
publication date: 2010-10-30T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

The anti-migraine agent sumatriptan induces a calcium-dependent discharge in meningeal sensory neurons.
PubMed Identifier: 15194863
author list: Strassman AM, Levy D
published in: Neuroreport
information resource reference: The anti-migraine agent sumatriptan induces a calcium-dependent discharge in meningeal sensory neurons. Neuroreport. 2004 Jun 28; 15(9):1409-12.
journal title abbreviation: Neuroreport
publication date: 2004-06-28T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

The vascular theory of migraine: leave it or love it?
PubMed Identifier: 21520229
author list: Levy D, Burstein R
published in: Annals of neurology
information resource reference: The vascular theory of migraine: leave it or love it? Ann Neurol. 2011 Apr; 69(4):600-1.
journal title abbreviation: Ann Neurol
publication date: 2011-04-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Activation of the migraine pain pathway by cortical spreading depression: do we need more evidence?
PubMed Identifier: 21996564
author list: Levy D, Moskowitz MA, Noseda R, Burstein R
published in: Cephalalgia : an international journal of headache
information resource reference: Activation of the migraine pain pathway by cortical spreading depression: do we need more evidence? Cephalalgia. 2012 May; 32(7):581-2.
journal title abbreviation: Cephalalgia
publication date: 2011-10-13T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Transient action of the endothelial constitutive nitric oxide synthase (ecNOS) mediates the development of thermal hypersensitivity following peripheral nerve injury.
PubMed Identifier: 10947811
author list: Levy D, Tal M, Höke A, Zochodne DW
published in: The European journal of neuroscience
information resource reference: Transient action of the endothelial constitutive nitric oxide synthase (ecNOS) mediates the development of thermal hypersensitivity following peripheral nerve injury. Eur J Neurosci. 2000 Jul; 12(7):2323-32.
journal title abbreviation: Eur J Neurosci
publication date: 2000-07-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Intact mast cell content during mild head injury is required for development of latent pain sensitization: implications for mechanisms underlying post-traumatic headache.
PubMed Identifier: 30624345
author list: Bree D, Levy D
published in: Pain
information resource reference: Intact mast cell content during mild head injury is required for development of latent pain sensitization: implications for mechanisms underlying post-traumatic headache. Pain. 2019 05; 160(5):1050-1058.
journal title abbreviation: Pain
publication date: 2019-05-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Local action of the proinflammatory cytokines IL-1ß and IL-6 on intracranial meningeal nociceptors.
PubMed Identifier: 22144718
author list: Zhang X, Burstein R, Levy D
published in: Cephalalgia : an international journal of headache
information resource reference: Local action of the proinflammatory cytokines IL-1ß and IL-6 on intracranial meningeal nociceptors. Cephalalgia. 2012 Jan; 32(1):66-72.
journal title abbreviation: Cephalalgia
publication date: 2011-12-05T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Meninges
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Dura Mater
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Nociceptors
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Migraine Disorders
MeSH DescriptorUI: D008881
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Post-Traumatic Headache
MeSH DescriptorUI: D051298
MeSH semantic group name: Disorders
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Anaesthesia
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Nephrology
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Experimental Medicine
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Endocrinology
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Translational Research
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Beth Israel Deaconess Medical Center
type: Organization

Boston Children's Hospital
type: Organization

Harvard Medical School
type: Organization

Massachusetts General Hospital
type: Organization

Ayata, Cenk
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Xu, Xiang
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Birrane, Gabriel
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Moskowitz, Michael
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Authorship 127399
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linked author: Levy, Dan
linked information resource: Migraine pain and nociceptor activation--where do we stand?

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Burstein, Rami
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Denker, Bradley
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Woolf, Clifford
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type: Agent
type: Person
preferred title: Professor of Neurology

Andermann, Mark Lawrence
eCommons Login: AM99
first name: Mark Lawrence
last name: Andermann
full name: Mark Lawrence David Andermann, Ph.D.
has faculty rank: Full Professor
latitude: 42.33602040000000
longitude: -71.10343250000000
Person ID: 5792
person in primary position: Professor of Medicine
type: Agent
type: Person
preferred title: Professor of Medicine

Borsook, David
eCommons Login: DB12
first name: David
last name: Borsook
full name: David Borsook, M.B.,B.Ch., Ph.D.
has faculty rank: Full Professor
latitude: 42.39465440000000
longitude: -71.19567110000000
Person ID: 45543
person in primary position: Professor of Anaesthesia, Emeritus
type: Agent
type: Person
preferred title: Professor of Anaesthesia, Emeritus

Strassman, Andrew
eCommons Login: AMS3
first name: Andrew
last name: Strassman
full name: Andrew Mark Strassman, Ph.D.
has faculty rank: Associate Professor
latitude: 42.34022770000000
longitude: -71.10585400000000
Person ID: 21556
person in primary position: Associate Professor of Anaesthesia
type: Agent
type: Person
preferred title: Associate Professor of Anaesthesia

Tenen, Daniel
eCommons Login: DGT1
first name: Daniel
last name: Tenen
full name: Daniel Geoffrey Tenen, M.D.
has faculty rank: Full Professor
latitude: 42.33837200000000
longitude: -71.10326900000000
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 63164
person in primary position: Professor of Medicine
type: Agent
type: Person
preferred title: Professor of Medicine

Authorship 136011
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Disruption of communication between peripheral and central trigeminovascular neurons mediates the antimigraine action of 5HT 1B/1D receptor agonists.

Authorship 1201833
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Intact mast cell content during mild head injury is required for development of latent pain sensitization: implications for mechanisms underlying post-traumatic headache.

Bone Anabolic Response in the Calvaria Following Mild Traumatic Brain Injury is Mediated by the Cannabinoid-1 Receptor.
PubMed Identifier: 31700010
author list: Eger M, Bader M, Bree D, Hadar R, Nemirovski A, Tam J, Levy D, Pick CG, Gabet Y
published in: Scientific reports
information resource reference: Bone Anabolic Response in the Calvaria Following Mild Traumatic Brain Injury is Mediated by the Cannabinoid-1 Receptor. Sci Rep. 2019 11 07; 9(1):16196.
journal title abbreviation: Sci Rep
publication date: 2019-11-07T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1203290
type: Authorship
author rank in publication: 7
linked author: Levy, Dan
linked information resource: Bone Anabolic Response in the Calvaria Following Mild Traumatic Brain Injury is Mediated by the Cannabinoid-1 Receptor.

Associate Professor of Anaesthesia
is primary position: true
position in department: Anaesthesia
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Anaesthesia
position in organization: Beth Israel Deaconess Medical Center

Associate Professor of Anaesthesia
is primary position: true
position in department: Anaesthesia
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Anaesthesia
position in organization: Beth Israel Deaconess Medical Center

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Beth Israel Deaconess Medical Center

Authorship 134165
type: Authorship
author rank in publication: 6
linked author: Levy, Dan
linked information resource: The alcohol hangover research group consensus statement on best practice in alcohol hangover research.

Authorship 125118
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Delayed peripheral nerve degeneration, regeneration, and pain in mice lacking inducible nitric oxide synthase.

Authorship 124369
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Local expression of inducible nitric oxide synthase in an animal model of neuropathic pain.

Authorship 167226
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Mast cell involvement in the pathophysiology of migraine headache: A hypothesis.

Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury.
PubMed Identifier: 32077327
author list: Bree D, Mackenzie K, Stratton J, Levy D
published in: Cephalalgia : an international journal of headache
information resource reference: Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury. Cephalalgia. 2020 06; 40(7):748-760.
journal title abbreviation: Cephalalgia
publication date: 2020-02-20T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1272102
type: Authorship
author rank in publication: 3
linked author: Levy, Dan
linked information resource: Increased severity of closed head injury or repetitive subconcussive head impacts enhances post-traumatic headache-like behaviors in a rat model.

Authorship 1272103
type: Authorship
author rank in publication: 4
linked author: Levy, Dan
linked information resource: Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury.

Authorship 1272104
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Different clinical phenotypes of persistent post-traumatic headache exhibit distinct sensory profiles.

Authorship 1272105
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Strides Toward Better Understanding of Post-Traumatic Headache Pathophysiology Using Animal Models.

Different clinical phenotypes of persistent post-traumatic headache exhibit distinct sensory profiles.
PubMed Identifier: 31847569
author list: Levy D, Gruener H, Riabinin M, Feingold Y, Schreiber S, Pick CG, Defrin R
published in: Cephalalgia : an international journal of headache
information resource reference: Different clinical phenotypes of persistent post-traumatic headache exhibit distinct sensory profiles. Cephalalgia. 2020 06; 40(7):675-688.
journal title abbreviation: Cephalalgia
publication date: 2019-12-17T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Increased severity of closed head injury or repetitive subconcussive head impacts enhances post-traumatic headache-like behaviors in a rat model.
PubMed Identifier: 32600065
author list: Bree D, Stratton J, Levy D
published in: Cephalalgia : an international journal of headache
information resource reference: Increased severity of closed head injury or repetitive subconcussive head impacts enhances post-traumatic headache-like behaviors in a rat model. Cephalalgia. 2020 10; 40(11):1224-1239.
journal title abbreviation: Cephalalgia
publication date: 2020-06-29T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Cortical-Meningeal Interactions Underlying Migraine Headache
end date: 2026-11-30
principal investigator name: LEVY, DAN
start date: 2020-12-15
type: Grant
sponsor award id: R01NS115972

Principal Investigator
type: Researcher Role
researcher role of: Levy, Dan
contributes to: Cortical-Meningeal Interactions Underlying Migraine Headache

Authorship 155468
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Response properties of dural nociceptors in relation to headache.

Astrocytes mediate migraine-related intracranial meningeal mechanical hypersensitivity.
PubMed Identifier: 34448752
author list: Zhao J, Blaeser AS, Levy D
published in: Pain
information resource reference: Astrocytes mediate migraine-related intracranial meningeal mechanical hypersensitivity. Pain. 2021 09 01; 162(9):2386-2396.
journal title abbreviation: Pain
publication date: 2021-09-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/203223252
type: Researcher Role
description: This proposal explores a peripheral neuroimmune mechanism of migraine, involving bidirectional communication between meningeal nociceptors and meningeal immune cells that drives migraine headache. If successful, the project could provide a dramatically better understanding of the role of neurogenic inflammation in migraine pathophysiology and serve as an experimental foundation for future explorations of mechanistic insights into meningeal neuroimmune crosstalk and further testing of specific immune cells and related proinflammatory mediators as potential therapeutic targets for migraine pain.
researcher role of: Levy, Dan
contributes to: Meningeal Nociceptor-Immune Signaling in Migraine

Authorship 1471593
type: Authorship
author rank in publication: 3
linked author: Levy, Dan
linked information resource: Astrocytes mediate migraine-related intracranial meningeal mechanical hypersensitivity.

Authorship 1471594
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Tamoxifen treatment for breast cancer: concept to gold standard.

Meningeal Nociceptor-Immune Signaling in Migraine
end date: 2024-08-31
principal investigator name: Levy Dan
start date: 2022-09-01
type: Grant
sponsor award id: 1R21NS130561-01

Tamoxifen treatment for breast cancer: concept to gold standard.
PubMed Identifier: 9065921
author list: Jordan VC
published in: Oncology (Williston Park, N.Y.)
information resource reference: Tamoxifen treatment for breast cancer: concept to gold standard. Oncology (Williston Park). 1997 Feb; 11(2 Suppl 1):7-13.
journal title abbreviation: Oncology (Williston Park)
publication date: 1997-02-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Trigeminal afferents sense locomotion-related meningeal deformations.
PubMed Identifier: 36384109
author list: Blaeser AS, Sugden AU, Zhao J, Carneiro-Nascimento S, Shipley FB, Carrié H, Andermann ML, Levy D
published in: Cell reports
information resource reference: Trigeminal afferents sense locomotion-related meningeal deformations. Cell Rep. 2022 11 15; 41(7):111648.
journal title abbreviation: Cell Rep
publication date: 2022-11-15T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Christensen, Sarah
eCommons Login: sac7953
first name: Sarah
last name: Christensen
full name: Sarah Christensen, D.V.M., Ph.D.
has faculty rank: Instructor
Person ID: 212303
person in primary position: Instructor in Anaesthesia
type: Agent
type: Person
preferred title: Instructor in Anaesthesia

Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Neurology
position in organization: Massachusetts General Hospital

Authorship 1530661
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Meningeal Mechanisms and the Migraine Connection.

Meningeal Mechanisms and the Migraine Connection.
PubMed Identifier: 36913712
author list: Levy D, Moskowitz MA
published in: Annual review of neuroscience
information resource reference: Meningeal Mechanisms and the Migraine Connection. Annu Rev Neurosci. 2023 07 10; 46:39-58.
journal title abbreviation: Annu Rev Neurosci
publication date: 2023-03-13T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 255604
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Increased mRNA expression of the B1 and B2 bradykinin receptors and antinociceptive effects of their antagonists in an animal model of neuropathic pain.

Authorship 276254
type: Authorship
author rank in publication: 3
linked author: Levy, Dan
linked information resource: Anti-migraine action of triptans is preceded by transient aggravation of headache caused by activation of meningeal nociceptors.

Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Neurology
position in organization: Massachusetts General Hospital

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Nephrology
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Beth Israel Deaconess Medical Center

Instructor in Anaesthesia
is primary position: true
position in department: Anaesthesia
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Instructor in Anaesthesia
position in organization: Beth Israel Deaconess Medical Center

Response Properties of Meningeal Afferents in Health and Migraine
end date: 2028-07-31
principal investigator name: LEVY, DAN
start date: 2023-08-18
type: Grant
sponsor award id: R01NS133625

Principal Investigator
type: Researcher Role
researcher role of: Levy, Dan
contributes to: Response Properties of Meningeal Afferents in Health and Migraine

Instructor in Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Instructor in Pathology
position in organization: Beth Israel Deaconess Medical Center

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Endocrinology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Beth Israel Deaconess Medical Center

Instructor in Medicine
is primary position: true
position in department: Medicine
position in division: Experimental Medicine
sort order: 1
type: Position
HR job title: Instructor in Medicine
position in organization: Beth Israel Deaconess Medical Center

Authorship 352964
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Sensitization of central trigeminovascular neurons: blockade by intravenous naproxen infusion.

Authorship 643730
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Mast cell degranulation distinctly activates trigemino-cervical and lumbosacral pain pathways and elicits widespread tactile pain hypersensitivity.

Authorship 644484
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Endogenous mechanisms underlying the activation and sensitization of meningeal nociceptors: the role of immuno-vascular interactions and cortical spreading depression.

Endogenous mechanisms underlying the activation and sensitization of meningeal nociceptors: the role of immuno-vascular interactions and cortical spreading depression.
PubMed Identifier: 22328144
author list: Levy D
published in: Current pain and headache reports
information resource reference: Endogenous mechanisms underlying the activation and sensitization of meningeal nociceptors: the role of immuno-vascular interactions and cortical spreading depression. Curr Pain Headache Rep. 2012 Jun; 16(3):270-7.
journal title abbreviation: Curr Pain Headache Rep
publication date: 2012-06-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Vascular extracellular signal-regulated kinase mediates migraine-related sensitization of meningeal nociceptors.
PubMed Identifier: 23447360
author list: Zhang X, Kainz V, Zhao J, Strassman AM, Levy D
published in: Annals of neurology
information resource reference: Vascular extracellular signal-regulated kinase mediates migraine-related sensitization of meningeal nociceptors. Ann Neurol. 2013 Jun; 73(6):741-50.
journal title abbreviation: Ann Neurol
publication date: 2013-06-17T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Meningeal brain borders and migraine headache genesis.
PubMed Identifier: 39304416
author list: Christensen SL, Levy D
published in: Trends in neurosciences
information resource reference: Meningeal brain borders and migraine headache genesis. Trends Neurosci. 2024 11; 47(11):918-932.
journal title abbreviation: Trends Neurosci
publication date: 2024-09-19T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 668877
type: Authorship
author rank in publication: 8
linked author: Levy, Dan
linked information resource: Na,K-ATPase alpha isoforms at the blood-cerebrospinal fluid-trigeminal nerve and blood-retina interfaces in the rat.

Authorship 668878
type: Authorship
author rank in publication: 5
linked author: Levy, Dan
linked information resource: Vascular extracellular signal-regulated kinase mediates migraine-related sensitization of meningeal nociceptors.

Authorship 668879
type: Authorship
author rank in publication: 3
linked author: Levy, Dan
linked information resource: Local action of the proinflammatory cytokines IL-1ß and IL-6 on intracranial meningeal nociceptors.

Authorship 668880
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Activation of the migraine pain pathway by cortical spreading depression: do we need more evidence?

Authorship 668881
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: The vascular theory of migraine: leave it or love it?

Authorship 668882
type: Authorship
author rank in publication: 4
linked author: Levy, Dan
linked information resource: Tumor necrosis factor-a induces sensitization of meningeal nociceptors mediated via local COX and p38 MAP kinase actions.

Authorship 668883
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Activation of central trigeminovascular neurons by cortical spreading depression.

Na,K-ATPase alpha isoforms at the blood-cerebrospinal fluid-trigeminal nerve and blood-retina interfaces in the rat.
PubMed Identifier: 23497725
author list: Arakaki X, McCleary P, Techy M, Chiang J, Kuo L, Fonteh AN, Armstrong B, Levy D, Harrington MG
published in: Fluids and barriers of the CNS
information resource reference: Na,K-ATPase alpha isoforms at the blood-cerebrospinal fluid-trigeminal nerve and blood-retina interfaces in the rat. Fluids Barriers CNS. 2013 Mar 14; 10(1):14.
journal title abbreviation: Fluids Barriers CNS
publication date: 2013-03-14T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 58361
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: NO pain: potential roles of nitric oxide in neuropathic pain.

Authorship 236296
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Calcitonin gene-related peptide does not excite or sensitize meningeal nociceptors: implications for the pathophysiology of migraine.

Professor of Anaesthesia, Emeritus
is primary position: true
position in department: Emeritus
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Anaesthesia, Emeritus
position in organization: Harvard Medical School

Authorship 270268
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Modulation of dural nociceptor mechanosensitivity by the nitric oxide-cyclic GMP signaling cascade.

Authorship 1773364
type: Authorship
author rank in publication: 8
linked author: Levy, Dan
linked information resource: Trigeminal afferents sense locomotion-related meningeal deformations.

Authorship 1768141
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Meningeal brain borders and migraine headache genesis.

Authorship 1821859
type: Authorship
author rank in publication: 3
linked author: Levy, Dan
linked information resource: Meningeal P2X7 Signaling Mediates Migraine-Related Intracranial Mechanical Hypersensitivity.

Authorship 1838882
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.

Meningeal P2X7 Signaling Mediates Migraine-Related Intracranial Mechanical Hypersensitivity.
PubMed Identifier: 37487740
author list: Zhao J, Harrison S, Levy D
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Meningeal P2X7 Signaling Mediates Migraine-Related Intracranial Mechanical Hypersensitivity. J Neurosci. 2023 08 16; 43(33):5975-5985.
journal title abbreviation: J Neurosci
publication date: 2023-07-24T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.
PubMed Identifier: 30744809
author list: Kirkland D, Levy DD, LeBaron MJ, Aardema MJ, Beevers C, Bhalli J, Douglas GR, Escobar PA, Farabaugh CS, Guerard M, Johnson GE, Kulkarni R, Le Curieux F, Long AS, Lott J, Lovell DP, Luijten M, Marchetti F, Nicolette JJ, Pfuhler S, Roberts DJ, Stankowski LF, Thybaud V, Weiner SK, Williams A, Witt KL, Young R
published in: Mutation research. Genetic toxicology and environmental mutagenesis
information resource reference: A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals. Mutat Res Genet Toxicol Environ Mutagen. 2019 Mar; 839:21-35.
journal title abbreviation: Mutat Res Genet Toxicol Environ Mutagen
publication date: 2019-01-18T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

John Hedley-Whyte Professor of Anaesthesia
is primary position: true
position in department: Anaesthesia
position in division: Translational Research
sort order: 1
type: Position
HR job title: John Hedley-Whyte Professor of Anaesthesia
position in organization: Beth Israel Deaconess Medical Center

Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Neurology
position in organization: Boston Children's Hospital

Selective inhibition of meningeal nociceptors by botulinum neurotoxin type A: therapeutic implications for migraine and other pains.
PubMed Identifier: 24694964
author list: Burstein R, Zhang X, Levy D, Aoki KR, Brin MF
published in: Cephalalgia : an international journal of headache
information resource reference: Selective inhibition of meningeal nociceptors by botulinum neurotoxin type A: therapeutic implications for migraine and other pains. Cephalalgia. 2014 Oct; 34(11):853-69.
journal title abbreviation: Cephalalgia
publication date: 2014-04-02T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 758898
type: Authorship
author rank in publication: 3
linked author: Levy, Dan
linked information resource: Selective inhibition of meningeal nociceptors by botulinum neurotoxin type A: therapeutic implications for migraine and other pains.

Authorship 758899
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Influence of sex, estrous cycle, and estrogen on intracranial dural mast cells.

Authorship 758900
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Mechanical response properties of A and C primary afferent neurons innervating the rat intracranial dura.

Authorship 758901
type: Authorship
author rank in publication: 6
linked author: Levy, Dan
linked information resource: Mild closed head injury promotes a selective trigeminal hypernociception: implications for the acute emergence of post-traumatic headache.

Authorship 758902
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: The sensory innervation of the calvarial periosteum is nociceptive and contributes to headache-like behavior.

The sensory innervation of the calvarial periosteum is nociceptive and contributes to headache-like behavior.
PubMed Identifier: 24769138
author list: Zhao J, Levy D
published in: Pain
information resource reference: The sensory innervation of the calvarial periosteum is nociceptive and contributes to headache-like behavior. Pain. 2014 Jul; 155(7):1392-1400.
journal title abbreviation: Pain
publication date: 2014-04-24T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Influence of sex, estrous cycle, and estrogen on intracranial dural mast cells.
PubMed Identifier: 22833613
author list: Boes T, Levy D
published in: Cephalalgia : an international journal of headache
information resource reference: Influence of sex, estrous cycle, and estrogen on intracranial dural mast cells. Cephalalgia. 2012 Sep; 32(12):924-31.
journal title abbreviation: Cephalalgia
publication date: 2012-07-24T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Mild closed head injury promotes a selective trigeminal hypernociception: implications for the acute emergence of post-traumatic headache.
PubMed Identifier: 25168788
author list: Benromano T, Defrin R, Ahn AH, Zhao J, Pick CG, Levy D
published in: European journal of pain (London, England)
information resource reference: Mild closed head injury promotes a selective trigeminal hypernociception: implications for the acute emergence of post-traumatic headache. Eur J Pain. 2015 May; 19(5):621-8.
journal title abbreviation: Eur J Pain
publication date: 2014-08-29T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 74396
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Transient action of the endothelial constitutive nitric oxide synthase (ecNOS) mediates the development of thermal hypersensitivity following peripheral nerve injury.

Authorship 475192
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Sensitization of meningeal nociceptors: inhibition by naproxen.

Authorship 96318
type: Authorship
author rank in publication: 5
linked author: Levy, Dan
linked information resource: Axon diameters and intradural trajectories of the dural innervation in the rat.

Authorship 235343
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Effects of sensitization of trigeminovascular neurons to triptan therapy during migraine.

Authorship 68604
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Evidence for nitric oxide and nitric oxide synthase activity in proximal stumps of transected peripheral nerves.

Authorship 438494
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Nitric oxide in damage, disease and repair of the peripheral nervous system.

Authorship 564690
type: Authorship
author rank in publication: 4
linked author: Levy, Dan
linked information resource: Sensitization and activation of intracranial meningeal nociceptors by mast cell mediators.

Authorship 337378
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: The anti-migraine agent sumatriptan induces a calcium-dependent discharge in meningeal sensory neurons.

Authorship 489890
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Mast cell degranulation activates a pain pathway underlying migraine headache.

Authorship 292467
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Terminating migraine with allodynia and ongoing central sensitization using parenteral administration of COX1/COX2 inhibitors.

Responses of dural mast cells in concussive and blast models of mild traumatic brain injury in mice: Potential implications for post-traumatic headache.
PubMed Identifier: 26566937
author list: Levy D, Edut S, Baraz-Goldstein R, Rubovitch V, Defrin R, Bree D, Gariepy H, Zhao J, Pick CG
published in: Cephalalgia : an international journal of headache
information resource reference: Responses of dural mast cells in concussive and blast models of mild traumatic brain injury in mice: Potential implications for post-traumatic headache. Cephalalgia. 2016 Sep; 36(10):915-23.
journal title abbreviation: Cephalalgia
publication date: 2015-11-12T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 523560
type: Authorship
author rank in publication: 6
linked author: Levy, Dan
linked information resource: Localization of COX-1 and COX-2 in the intracranial dura mater of the rat.

Associate Professor
sort order: 1
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Instructor
sort order: 4
type: Faculty Rank

Authorship 492544
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: A critical view on the role of migraine triggers in the genesis of migraine pain.

Cranial dural permeability of inflammatory nociceptive mediators: Potential implications for animal models of migraine.
PubMed Identifier: 27493234
author list: Zhao J, Bree D, Harrington MG, Strassman AM, Levy D
published in: Cephalalgia : an international journal of headache
information resource reference: Cranial dural permeability of inflammatory nociceptive mediators: Potential implications for animal models of migraine. Cephalalgia. 2017 Oct; 37(11):1017-1025.
journal title abbreviation: Cephalalgia
publication date: 2016-08-19T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 908179
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Responses of dural mast cells in concussive and blast models of mild traumatic brain injury in mice: Potential implications for post-traumatic headache.

Authorship 520303
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Migraine pain, meningeal inflammation, and mast cells.

Calvarial periosteal afferents in post-traumatic headache
end date: 2014-08-31
principal investigator name: LEVY, DAN
start date: 2011-09-01
type: Grant
sponsor award id: R21NS077882

MECHANISMS OF CSD-EVOKED PERSISTENT ACTIVATION OF MENINGEAL NOCICEPTORS
end date: 2024-05-31
principal investigator name: LEVY, DAN
start date: 2013-07-15
type: Grant
sponsor award id: R01NS078263

Estrogen Withdrawal and Dural Mast Cells: Implication for Menstrual Migraine
end date: 2012-02-28
principal investigator name: LEVY, DAN
start date: 2009-03-01
type: Grant
sponsor award id: R21NS061116

Peripheral Mechanisms of Posttraumatic Headache
end date: 2020-05-31
principal investigator name: LEVY, DAN
start date: 2014-08-15
type: Grant
sponsor award id: R01NS086830

Mechanisms of Alcohol Hangover Headache
end date: 2015-01-31
principal investigator name: LEVY, DAN
start date: 2012-02-10
type: Grant
sponsor award id: R21AA020305

Mast Cells: Role in the Pathophysiology of Headache
end date: 2010-03-31
principal investigator name: LEVY, DAN
start date: 2004-04-01
type: Grant
sponsor award id: R01NS046502

Principal Investigator
type: Researcher Role
researcher role of: Levy, Dan
contributes to: Mechanisms of Alcohol Hangover Headache

Principal Investigator
type: Researcher Role
researcher role of: Levy, Dan
contributes to: MECHANISMS OF CSD-EVOKED PERSISTENT ACTIVATION OF MENINGEAL NOCICEPTORS

Principal Investigator
type: Researcher Role
researcher role of: Levy, Dan
contributes to: Peripheral Mechanisms of Posttraumatic Headache

Principal Investigator
type: Researcher Role
researcher role of: Levy, Dan
contributes to: Estrogen Withdrawal and Dural Mast Cells: Implication for Menstrual Migraine

Principal Investigator
type: Researcher Role
researcher role of: Levy, Dan
contributes to: Mast Cells: Role in the Pathophysiology of Headache

Principal Investigator
type: Researcher Role
researcher role of: Levy, Dan
contributes to: Calvarial periosteal afferents in post-traumatic headache

Authorship 356843
type: Authorship
author rank in publication: 1
linked author: Levy, Dan
linked information resource: Distinct sensitizing effects of the cAMP-PKA second messenger cascade on rat dural mechanonociceptors.

Authorship 547052
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Activation of meningeal nociceptors by cortical spreading depression: implications for migraine with aura.

Development of CGRP-dependent pain and headache related behaviours in a rat model of concussion: Implications for mechanisms of post-traumatic headache.
PubMed Identifier: 27899434
author list: Bree D, Levy D
published in: Cephalalgia : an international journal of headache
information resource reference: Development of CGRP-dependent pain and headache related behaviours in a rat model of concussion: Implications for mechanisms of post-traumatic headache. Cephalalgia. 2018 02; 38(2):246-258.
journal title abbreviation: Cephalalgia
publication date: 2016-12-07T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 364221
type: Authorship
author rank in publication: 2
linked author: Levy, Dan
linked information resource: Modulation of meningeal nociceptors mechanosensitivity by peripheral proteinase-activated receptor-2: the role of mast cells.

Distinct sensitizing effects of the cAMP-PKA second messenger cascade on rat dural mechanonociceptors.
PubMed Identifier: 11790814
author list: Levy D, Strassman AM
published in: The Journal of physiology
information resource reference: Distinct sensitizing effects of the cAMP-PKA second messenger cascade on rat dural mechanonociceptors. J Physiol. 2002 Jan 15; 538(Pt 2):483-93.
journal title abbreviation: J Physiol
publication date: 2002-01-15T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Anti-migraine action of triptans is preceded by transient aggravation of headache caused by activation of meningeal nociceptors.
PubMed Identifier: 15836966
author list: Burstein R, Jakubowski M, Levy D
published in: Pain
information resource reference: Anti-migraine action of triptans is preceded by transient aggravation of headache caused by activation of meningeal nociceptors. Pain. 2005 May; 115(1-2):21-8.
journal title abbreviation: Pain
publication date: 2005-05-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Axon diameters and intradural trajectories of the dural innervation in the rat.
PubMed Identifier: 15116396
author list: Strassman AM, Weissner W, Williams M, Ali S, Levy D
published in: The Journal of comparative neurology
information resource reference: Axon diameters and intradural trajectories of the dural innervation in the rat. J Comp Neurol. 2004 May 31; 473(3):364-76.
journal title abbreviation: J Comp Neurol
publication date: 2004-05-31T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Increased mRNA expression of the B1 and B2 bradykinin receptors and antinociceptive effects of their antagonists in an animal model of neuropathic pain.
PubMed Identifier: 10812256
author list: Levy D, Zochodne DW
published in: Pain
information resource reference: Increased mRNA expression of the B1 and B2 bradykinin receptors and antinociceptive effects of their antagonists in an animal model of neuropathic pain. Pain. 2000 Jun; 86(3):265-271.
journal title abbreviation: Pain
publication date: 2000-06-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Sensitization and activation of intracranial meningeal nociceptors by mast cell mediators.
PubMed Identifier: 17483291
author list: Zhang XC, Strassman AM, Burstein R, Levy D
published in: The Journal of pharmacology and experimental therapeutics
information resource reference: Sensitization and activation of intracranial meningeal nociceptors by mast cell mediators. J Pharmacol Exp Ther. 2007 Aug; 322(2):806-12.
journal title abbreviation: J Pharmacol Exp Ther
publication date: 2007-05-04T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Modulation of dural nociceptor mechanosensitivity by the nitric oxide-cyclic GMP signaling cascade.
PubMed Identifier: 15056690
author list: Levy D, Strassman AM
published in: Journal of neurophysiology
information resource reference: Modulation of dural nociceptor mechanosensitivity by the nitric oxide-cyclic GMP signaling cascade. J Neurophysiol. 2004 Aug; 92(2):766-72.
journal title abbreviation: J Neurophysiol
publication date: 2004-03-31T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Response properties of dural nociceptors in relation to headache.
PubMed Identifier: 16492942
author list: Strassman AM, Levy D
published in: Journal of neurophysiology
information resource reference: Response properties of dural nociceptors in relation to headache. J Neurophysiol. 2006 Mar; 95(3):1298-306.
journal title abbreviation: J Neurophysiol
publication date: 2006-03-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

NO pain: potential roles of nitric oxide in neuropathic pain.
PubMed Identifier: 17129298
author list: Levy D, Zochodne DW
published in: Pain practice : the official journal of World Institute of Pain
information resource reference: NO pain: potential roles of nitric oxide in neuropathic pain. Pain Pract. 2004 Mar; 4(1):11-8.
journal title abbreviation: Pain Pract
publication date: 2004-03-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Local expression of inducible nitric oxide synthase in an animal model of neuropathic pain.
PubMed Identifier: 10076904
author list: Levy D, Höke A, Zochodne DW
published in: Neuroscience letters
information resource reference: Local expression of inducible nitric oxide synthase in an animal model of neuropathic pain. Neurosci Lett. 1999 Feb 05; 260(3):207-9.
journal title abbreviation: Neurosci Lett
publication date: 1999-02-05T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Local nitric oxide synthase activity in a model of neuropathic pain.
PubMed Identifier: 9751155
author list: Levy D, Zochodne DW
published in: The European journal of neuroscience
information resource reference: Local nitric oxide synthase activity in a model of neuropathic pain. Eur J Neurosci. 1998 May; 10(5):1846-55.
journal title abbreviation: Eur J Neurosci
publication date: 1998-05-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Mast cell degranulation distinctly activates trigemino-cervical and lumbosacral pain pathways and elicits widespread tactile pain hypersensitivity.
PubMed Identifier: 22019552
author list: Levy D, Kainz V, Burstein R, Strassman AM
published in: Brain, behavior, and immunity
information resource reference: Mast cell degranulation distinctly activates trigemino-cervical and lumbosacral pain pathways and elicits widespread tactile pain hypersensitivity. Brain Behav Immun. 2012 Feb; 26(2):311-7.
journal title abbreviation: Brain Behav Immun
publication date: 2011-10-12T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Activation of central trigeminovascular neurons by cortical spreading depression.
PubMed Identifier: 21416489
author list: Zhang X, Levy D, Kainz V, Noseda R, Jakubowski M, Burstein R
published in: Annals of neurology
information resource reference: Activation of central trigeminovascular neurons by cortical spreading depression. Ann Neurol. 2011 May; 69(5):855-65.
journal title abbreviation: Ann Neurol
publication date: 2011-03-17T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Chronic two-photon calcium imaging of intracranial meningeal afferents in awake behaving mice
end date: 2020-03-31
principal investigator name: LEVY, DAN
start date: 2017-04-01
type: Grant
sponsor award id: R21NS101405

Principal Investigator
type: Researcher Role
researcher role of: Levy, Dan
contributes to: Chronic two-photon calcium imaging of intracranial meningeal afferents in awake behaving mice

Effects of sensitization of trigeminovascular neurons to triptan therapy during migraine.
PubMed Identifier: 16141951
author list: Burstein R, Levy D, Jakubowski M
published in: Revue neurologique
information resource reference: Effects of sensitization of trigeminovascular neurons to triptan therapy during migraine. Rev Neurol (Paris). 2005 Jul; 161(6-7):658-60.
journal title abbreviation: Rev Neurol (Paris)
publication date: 2005-07-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Calcitonin gene-related peptide does not excite or sensitize meningeal nociceptors: implications for the pathophysiology of migraine.
PubMed Identifier: 16240341
author list: Levy D, Burstein R, Strassman AM
published in: Annals of neurology
information resource reference: Calcitonin gene-related peptide does not excite or sensitize meningeal nociceptors: implications for the pathophysiology of migraine. Ann Neurol. 2005 Nov; 58(5):698-705.
journal title abbreviation: Ann Neurol
publication date: 2005-11-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Sensitization of central trigeminovascular neurons: blockade by intravenous naproxen infusion.
PubMed Identifier: 17651900
author list: Jakubowski M, Levy D, Kainz V, Zhang XC, Kosaras B, Burstein R
published in: Neuroscience
information resource reference: Sensitization of central trigeminovascular neurons: blockade by intravenous naproxen infusion. Neuroscience. 2007 Aug 24; 148(2):573-83.
journal title abbreviation: Neuroscience
publication date: 2007-07-25T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Mast cell degranulation activates a pain pathway underlying migraine headache.
PubMed Identifier: 17459586
author list: Levy D, Burstein R, Kainz V, Jakubowski M, Strassman AM
published in: Pain
information resource reference: Mast cell degranulation activates a pain pathway underlying migraine headache. Pain. 2007 Jul; 130(1-2):166-76.
journal title abbreviation: Pain
publication date: 2007-04-24T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanical response properties of A and C primary afferent neurons innervating the rat intracranial dura.
PubMed Identifier: 12466427
author list: Levy D, Strassman AM
published in: Journal of neurophysiology
information resource reference: Mechanical response properties of A and C primary afferent neurons innervating the rat intracranial dura. J Neurophysiol. 2002 Dec; 88(6):3021-31.
journal title abbreviation: J Neurophysiol
publication date: 2002-12-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

The alcohol hangover research group consensus statement on best practice in alcohol hangover research.
PubMed Identifier: 20712593
author list: Verster JC, Stephens R, Penning R, Rohsenow D, McGeary J, Levy D, McKinney A, Finnigan F, Piasecki TM, Adan A, Batty GD, Fliervoet LA, Heffernan T, Howland J, Kim DJ, Kruisselbrink LD, Ling J, McGregor N, Murphy RJ, van Nuland M, Oudelaar M, Parkes A, Prat G, Reed N, Slutske WS, Smith G, Young M
published in: Current drug abuse reviews
information resource reference: The alcohol hangover research group consensus statement on best practice in alcohol hangover research. Curr Drug Abuse Rev. 2010 Jun; 3(2):116-26.
journal title abbreviation: Curr Drug Abuse Rev
publication date: 2010-06-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

A critical view on the role of migraine triggers in the genesis of migraine pain.
PubMed Identifier: 19545256
author list: Levy D, Strassman AM, Burstein R
published in: Headache
information resource reference: A critical view on the role of migraine triggers in the genesis of migraine pain. Headache. 2009 Jun; 49(6):953-7.
journal title abbreviation: Headache
publication date: 2009-06-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Localization of COX-1 and COX-2 in the intracranial dura mater of the rat.
PubMed Identifier: 19444941
author list: Zhang XC, Kainz V, Jakubowski M, Burstein R, Strassman A, Levy D
published in: Neuroscience letters
information resource reference: Localization of COX-1 and COX-2 in the intracranial dura mater of the rat. Neurosci Lett. 2009 Mar 06; 452(1):33-6.
journal title abbreviation: Neurosci Lett
publication date: 2009-03-06T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

330 Brookline Ave
type: Address
address line 1: Beth Israel Deaconess Medical Center
address line 2: Anesthesia & Critical Care, DA 717
address line 3: 330 Brookline Ave
city: Boston
postal code: 02215
state or province: MA

Sensitization of meningeal nociceptors: inhibition by naproxen.
PubMed Identifier: 18333963
author list: Levy D, Zhang XC, Jakubowski M, Burstein R
published in: The European journal of neuroscience
information resource reference: Sensitization of meningeal nociceptors: inhibition by naproxen. Eur J Neurosci. 2008 Feb; 27(4):917-22.
journal title abbreviation: Eur J Neurosci
publication date: 2008-02-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Disruption of communication between peripheral and central trigeminovascular neurons mediates the antimigraine action of 5HT 1B/1D receptor agonists.
PubMed Identifier: 15016917
author list: Levy D, Jakubowski M, Burstein R
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Disruption of communication between peripheral and central trigeminovascular neurons mediates the antimigraine action of 5HT 1B/1D receptor agonists. Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12):4274-9.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2004-03-11T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Evidence for nitric oxide and nitric oxide synthase activity in proximal stumps of transected peripheral nerves.
PubMed Identifier: 10391455
author list: Zochodne DW, Levy D, Zwiers H, Sun H, Rubin I, Cheng C, Lauritzen M
published in: Neuroscience
information resource reference: Evidence for nitric oxide and nitric oxide synthase activity in proximal stumps of transected peripheral nerves. Neuroscience. 1999; 91(4):1515-27.
journal title abbreviation: Neuroscience
publication date: 1999-01-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource