Title Associate Professor of Surgery Institution Beth Israel Deaconess Medical Center Address Beth Israel Deaconess Med Ctr Da-881 330 Brookline Ave Boston MA 02215
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Biography
Nanjing University, Nanjing, China | B.S. | 07/1984 | Analytical Chemistry |
Nanjing University, Nanjing, China | M.S. | 11/1987 | Environmental Sciences/Nutrition |
University of Illinois, Urbana-Champaign, IL | Ph.D. | 10/1994 | Nutritional Sciences |
Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA | Postdoc. Fellow | 07/1996 | Bionutrition and Cancer Prevention |
1991 - 1992
University Fellowship
1994
Graduate Student Award in Vitamin Research
1996 - 1999
National Individual Research Service Award
2015 - 2018
Chair (Elect, Past), Diet & Cancer Research Interest Section
2020 - 2022
Member, Board of Directors
2017 - 2021
Vice Chairperson, Board of Specialty Committee of Breast Diseases
Overview
The laboratory prioritizes investigating the most complex issues dealing with nutrition and health. Our research aims to identify bioactive dietary, nutritional and natural botanical components for the prevention and treatment of certain chronic diseases, such as cancer, metabolic disorders, and neurological-psychiatric diseases. We apply integrated research platforms by establishing both in vitro and clinically relevant animal models for chronic diseases and utilizing advanced techniques in cellular and molecular biology and epigenetics to identify effective and safe regimens for the prevention and therapy of diseases and to elucidate the mechanisms of action of candidate regimens.
By using integrated approaches, we have made significant achievements in identifying candidate regimens for the prevention of certain chronic diseases. We were the first group to demonstrate the synergistic combination effect between soybean and tea active components on preventing breast and prostate cancers. We were also among the first few research groups to propose metabolic syndrome as a potential etiological risk factor for the development and progression of several types of cancer, and in particular, maternal metabolic disorder status as a risk factor for cancer in offspring. We are applying cellular function-guided extraction, fractionation, and purification strategies to identify active components from botanicals and Chinese herbal medicines for targeting disease-specific cellular processes, such as those involved in cancer stem cells, preneoplastic transformation, and aging-associated cognitive impairment. Our research findings can provide essential experimental evidence to demonstrate the efficacy and safety of candidate regimens, and support translation into future clinical investigations.
- diet/nutrition, phytochemical, nutraceuticals, cancer, metabolic disorders, aging, cognition
- Breast cancer, prostate cancer, bladder cancer, inflammation, antioxidant
Research
The research activities and funding listed below are automatically derived from
NIH ExPORTER and other sources, which might result in incorrect or missing items.
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(Chaikof, Elliot)
Apr 1, 2022 - Mar 31, 2024
Effects of acai berry extract on delaying aging-associated cognitive impairment
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(ZHOU, JIN-RONG)
Mar 1, 2022 - Mar 31, 2024
Nichimo Biotics Co., Japan
Evaluation of Immunbalance as a lifespan-prolonging nutraceutical
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(ZHOU, JIN-RONG)
Nov 1, 2018 - Oct 31, 2021
Vitamin World (China) Ltd
Evaluation of anti-oxidative activities of Acai preparations
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(ZHOU, JIN-RONG)
Jun 30, 2018 - Jun 29, 2020
Hunan Yandi Bioengineering Co., China
Effects of Nostoc on glucose homeostasis, digestive health and cognition
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(ZHOU, JIN-RONG)
Feb 16, 2018 - Feb 15, 2019
Nichimo Biotics Co. and Lifetrade Co., Japan
Effects of bioactive agents on cognition
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(ZHOU, JIN-RONG)
Dec 1, 2017 - Nov 30, 2019
Jinghua Pharmaceuticals, Co., China
Effects of Wang-Shi-Bo-Chi-Wan (WSBCW) on gastrointestinal functions and its mechanisms of action
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(ZHOU, JIN-RONG)
Dec 20, 2016 - Dec 31, 2022
Kanion Pharmaceuticals, Co., China
Effects of Epimedium Flavonoids Extract (EFE) on Osteoporosis and Breast Cancer
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(ZHOU, JIN-RONG)
Nov 30, 2015 - Nov 29, 2017
Nichimo Biotics Co., and Lifetrade Co., Japan
Effects of bioactive agents on prevention of chronic kidney disease
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(Zhou, Jin-Rong)
May 27, 2015 - May 26, 2017
Maternal anti-inflammatory diet for prevention of autism in offspring
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(Zhou, Jin-Rong)
Dec 27, 2013 - Dec 26, 2015
Nichimo Biotics Co., Japan
Effects of fermented soy germ bioactive components on prostate cancer stem cell self-renewal
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R03CA159348
(ZHOU, JIN-RONG)
Jul 5, 2011 - Jun 30, 2013
Tanshinones for prevention of bladder cancer progression
Role: Principal Investigator
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R21CA153355
(ZHOU, JIN-RONG)
Jul 1, 2011 - Jun 30, 2014
Targeting prostate cancer stem cells to delay prostate cancer progression
Role: Principal Investigator
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R21CA127794
(ZHOU, JIN-RONG)
Apr 8, 2008 - Mar 31, 2011
Metabolic Syndrome as Pancreatic Cancer Etiology
Role: Principal Investigator
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R21CA133865
(ZHOU, JIN-RONG)
Sep 14, 2007 - Aug 31, 2010
Oldenlandia diffusa for prostate cancer treatment
Role: Principal Investigator
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R03CA130131
(ZHOU, JIN-RONG)
Sep 1, 2007 - Aug 31, 2010
Parental metabolic status and offspring cancer risks
Role: Principal Investigator
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R03CA130133
(ZHOU, JIN-RONG)
Sep 1, 2007 - Feb 28, 2010
Synergy between phytochemicals for prostate cancer prevention
Role: Principal Investigator
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R03CA112640
(ZHOU, JIN-RONG)
Sep 30, 2004 - Aug 31, 2007
Prevention of bladder cancer progression by sulforaphane
Role: Principal Investigator
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R03CA112644
(ZHOU, JIN-RONG)
Sep 21, 2004 - Aug 31, 2007
Genistien and prevention of HER2-overexpressing breast *
Role: Principal Investigator
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R01CA092546
(ZHOU, JIN-RONG)
Jun 1, 2003 - May 31, 2008
Chemoprevention of Bladder CA by soybean bioactive comp.
Role: Principal Investigator
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R03CA101041
(ZHOU, JIN-RONG)
May 1, 2003 - Apr 30, 2005
Genes Modulated by Soy in Prostate Cancer Progression
Role: Principal Investigator
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R01AT000863
(ZHOU, JIN-RONG)
Sep 12, 2001 - May 31, 2005
Interactions Between Dietary Soy Components &Tamoxifen
Role: Principal Investigator
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R01CA078521
(ZHOU, JIN-RONG)
Jun 1, 1999 - Nov 30, 2002
DIETARY SOYBEAN COMPONENTS AFFECT ON PROSTATE CANCER PRO
Role: Principal Investigator
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F32CA071161
(ZHOU, JIN-RONG)
Oct 29, 1996
DIETARY SOY ISOFLAVONES AND PROSTATE CANCER PROGRESSION
Role: Principal Investigator
Bibliographic
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